SCHEMBL26164174

SCHEMBL26164174

Cc1cccc(-c2ccccc2-c2cccc([N+](=O)[O-])c2F)c1-c1cccc(-c2ccccc2)c1N

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
TDP1 Q9NUW8 4/20 0.47
HSD17B10 Q99714 1/20 0.42
TSHR P16473 2/20 0.40
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
S100A4 P26447 2/20 0.37
PTPRC P08575 1/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
MAOA P21397 1/20 0.35
KLK3 P07288 1/20 0.35
PSMD14 O00487 1/20 0.34
PRKACA P17612 1/20 0.34
CASP6 P55212 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29565552 0.88 ALDH1A1 (0.56) ALDH1A1TDP1HSD17B10MGAMGAA
SCHEMBL26164145 0.88 ALDH1A1 (0.56) ALDH1A1TDP1HSD17B10MGAMGAA
SCHEMBL26167530 0.86 ALDH1A1 (0.45) ALDH1A1TDP1SMN1; SMN2L3MBTL1S100A4
SCHEMBL29565907 0.86 ALDH1A1 (0.45) ALDH1A1TDP1SMN1; SMN2L3MBTL1S100A4
SCHEMBL26164167 0.85 HSD17B10 (0.46) ALDH1A1TDP1HSD17B10TSHRLMNA
SCHEMBL1999472 0.78 ALDH1A1 (0.69) ALDH1A1TDP1HSD17B10TSHRL3MBTL1
SCHEMBL1251652 0.75 TDP1 (0.69) ALDH1A1TDP1HSD17B10TSHRSMN1; SMN2
SCHEMBL26164166 0.75 HSD17B10 (0.50) ALDH1A1TDP1HSD17B10TSHRLMNA
SCHEMBL31713028 0.74 S100A4 (0.45) ALDH1A1TDP1HSD17B10SMN1; SMN2MGAM
SCHEMBL29565972 0.74 PDE7A (0.46) ALDH1A1TDP1HSD17B10SMN1; SMN2MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167145-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167145-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP ALDH1A1 263/4885TDP1 1863/4885HSD17B10 1595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.