SCHEMBL2616753

SCHEMBL2616753

CO[Si](C)(CCCNC(=O)CCC(=O)O)OC

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
PHF8 Q9UPP1 3/20 0.40
KDM2A Q9Y2K7 3/20 0.40
EPHX2 P34913 3/20 0.39
KDM4E B2RXH2 3/20 0.38
LMNA P02545 2/20 0.38
CASP2 P42575 1/20 0.38
ADRA1A P35348 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KDM5C P41229 2/20 0.37
EGLN1 Q9GZT9 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MAPT P10636 1/20 0.37
SLC6A5 Q9Y345 1/20 0.37
HPGD P15428 1/20 0.37
KDM6B O15054 1/20 0.36
FOLH1 Q04609 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24844354 0.90 EPHX2 (0.50) TSHREPHX2KDM4ELMNAADRA1A
SCHEMBL17578483 0.85 TSHR (0.40) TSHRPHF8KDM2AEPHX2KDM4E
SCHEMBL2616751 0.84 TSHR (0.46) TSHRPHF8KDM2AEPHX2KDM4E
SCHEMBL2616752 0.83 EPHX2 (0.40) TSHRPHF8KDM2AEPHX2KDM4E
SCHEMBL29543014 0.83 TSHR (0.49) TSHRCASP2L3MBTL1MEN1KMT2A
SCHEMBL13587221 0.82 EPHX2 (0.42) TSHRPHF8KDM2AEPHX2KDM4E
SCHEMBL11905222 0.81 TSHR (0.38) TSHRADRA1APOLB
SCHEMBL16422336 0.80 TSHR (0.40) TSHRKDM4ELMNACASP2MEN1
SCHEMBL10136042 0.80 TSHR (0.36) TSHRPHF8KDM2AEPHX2KDM4E
SCHEMBL16613121 0.80 EPHX1 (0.35) TSHRKDM4EADRA1AEGLN1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492071-B2 Curable composition, color filter and process for production thereof, and solid-state imaging device FUJIFILM CORPORATION (JP) 2013-07-23 US disclosed
US-8492071-B2 Curable composition, color filter and process for production thereof, and solid-state imaging device FUJIFILM CORPORATION (JP) 2013-07-23 US disclosed
US-8182968-B2 Color filter and method for producing the same FUJIFILM CORPORATION (JP) 2012-05-22 US disclosed
US-8158307-B2 Forming first color pattern in repeating pattern on substrate; forming second color pattern on substrate; removal by dry etching; forming third color pattern FUJIFILM CORPORATION (JP) 2012-04-17 US disclosed
US-20110028587-A1 CURABLE COMPOSITION, COLOR FILTER AND PROCESS FOR PRODUCTION THEREOF, AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2011-02-03 US disclosed
US-20110028587-A1 CURABLE COMPOSITION, COLOR FILTER AND PROCESS FOR PRODUCTION THEREOF, AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2011-02-03 US disclosed
US-20080286665-A1 COLOR FILTER AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080206659-A1 COLOR FILTER AND METHOD OF MANUFACTURING THE SAME, AND SOLID-STATE IMAGE PICKUP ELEMENT FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed