SCHEMBL26168754

SCHEMBL26168754

c1ccc(-c2ccc3oc4cc(-c5nc(-c6ccccc6)nc(-c6cccc7oc8ccc(-c9ccc%10c%11cc(-c%12ccccc%12)ccc%11n(-c%11ccccc%11)c%10c9)cc8c67)n5)ccc4c3c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.31
SIRT1 Q96EB6 1/20 0.31
PLA2G2A P14555 1/20 0.31
PLA2G4A P47712 1/20 0.31
PIM1 P11309 1/20 0.31
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31
PIM3 Q86V86 1/20 0.31
PIM2 Q9P1W9 1/20 0.31
MMP12 P39900 1/20 0.30
MMP13 P45452 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
HPSE Q9Y251 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26168785 0.99 PLA2G2A (0.31) PLA2G2APLA2G4APIM1CSNK2A2CSNK2B
SCHEMBL26169017 0.98 PLA2G2A (0.33) SIRT2SIRT1PLA2G2APLA2G4APIM1
SCHEMBL26169222 0.98 PLA2G2A (0.33) SIRT2SIRT1PLA2G2APLA2G4APIM1
SCHEMBL26168517 0.98 PLA2G2A (0.33) SIRT2SIRT1PLA2G2APLA2G4APIM1
SCHEMBL23947829 0.97 SIRT2 (0.32) SIRT2SIRT1PLA2G2APLA2G4APIM1
SCHEMBL25504813 0.97 PLA2G2A (0.32) SIRT2SIRT1PLA2G2APLA2G4AMMP12
SCHEMBL26168487 0.97 PLA2G2A (0.33) SIRT2SIRT1PLA2G2APLA2G4APIM1
SCHEMBL23814075 0.97 PLA2G2A (0.33) SIRT2SIRT1PLA2G2APLA2G4APIM1
SCHEMBL26168740 0.96 ATM (0.34) SIRT2SIRT1PLA2G2APLA2G4APIM1
SCHEMBL26168738 0.96 ATM (0.34) SIRT2SIRT1PLA2G2APLA2G4APIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230172062-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-06-01 US disclosed
US-20230172062-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230172062-A1 ORGANIC ELECTROLUMINESCENT APPARATUS SLC29A1, SLC19A2, NUDT1 SIRT2 3104/4885SIRT1 3775/4885PLA2G2A 4486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.