Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 11/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26169926 | 0.94 | CPB2 (0.44) | CPB2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL26172465 | 0.93 | CPB2 (0.47) | CPB2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL26879069 | 0.91 | CPB2 (0.47) | CPB2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL26169977 | 0.89 | CPB2 (0.44) | CPB2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL24916226 | 0.85 | CPB2 (0.53) | CPB2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL26873245 | 0.84 | CPB2 (0.46) | CPB2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL26903709 | 0.82 | CPB2 (0.45) | CPB2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL26888060 | 0.81 | NMT1 (0.52) | CPB2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL26174195 | 0.80 | CPB2 (0.43) | CPB2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL26167562 | 0.78 | FURIN (0.36) | CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225661-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-11-23 | — | — | WO | disclosed |
| WO-2023102507-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-06-08 | — | — | WO | disclosed |