Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 8/20 | 0.52 |
| ▸ | NMT2 | O60551 | 7/20 | 0.52 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26890960 | 0.85 | NMT1 (0.52) | NMT1NMT2 | |
| SCHEMBL26903709 | 0.85 | CPB2 (0.45) | NMT1NMT2CPB2PSEN1PSEN2 | |
| SCHEMBL26174178 | 0.81 | CPB2 (0.48) | CPB2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL26174195 | 0.79 | CPB2 (0.43) | NMT1NMT2CPB2CHRNB2CHRNB4 | |
| SCHEMBL26172465 | 0.78 | CPB2 (0.47) | CPB2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL26172314 | 0.77 | CPB2 (0.47) | CPB2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL26879069 | 0.77 | CPB2 (0.47) | CPB2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL16359306 | 0.76 | NMT1 (0.54) | NMT1NMT2 | |
| SCHEMBL16359357 | 0.76 | NMT1 (0.54) | NMT1NMT2 | |
| SCHEMBL26170814 | 0.76 | CPB2 (0.46) | CPB2CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225661-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-11-23 | — | — | WO | disclosed |