SCHEMBL26178

SCHEMBL26178

CC(=O)[C@@]1(O)[C@H](O)C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SERPINA6 P08185 5/20 1.00
SHBG P04278 7/20 0.69
LMNA P02545 7/20 0.69
NR3C1 P04150 5/20 0.69
CYP2C19 P33261 4/20 0.69
SMN1; SMN2 Q16637 3/20 0.69
MAPT P10636 2/20 0.69
BLM P54132 2/20 0.69
MEN1 O00255 2/20 0.69
KMT2A Q03164 2/20 0.69
ADORA3 P0DMS8 1/20 0.69
MAPK3 P27361 1/20 0.69
SLC6A3 Q01959 1/20 0.69
CYP17A1 P05093 2/20 0.66
PGR P06401 4/20 0.65
ALDH1A1 P00352 1/20 0.65
ADRA1A P35348 1/20 0.65
HTR2B P41595 1/20 0.65
HSD17B10 Q99714 5/20 0.60
TSHR P16473 5/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11682243 1.00 SERPINA6 (1.00) SERPINA6SHBGLMNANR3C1CYP2C19
SCHEMBL3052566 1.00 SERPINA6 (1.00) SERPINA6SHBGLMNANR3C1CYP2C19
Acetic Acid SCHEMBL28423891 0.98 SERPINA6 (0.96) SERPINA6SHBGLMNANR3C1CYP2C19
SCHEMBL9221947 0.89 SERPINA6 (0.80) SERPINA6SHBGLMNANR3C1CYP2C19
SCHEMBL8755727 0.89 SERPINA6 (0.80) SERPINA6SHBGLMNANR3C1CYP2C19
SCHEMBL10868078 0.89 SERPINA6 (0.80) SERPINA6SHBGLMNANR3C1CYP2C19
Hydroxyprogesterone SCHEMBL23456341 0.82 LMNA (1.00) SERPINA6SHBGLMNANR3C1CYP2C19
Hydroxyprogesterone SCHEMBL3931615 0.82 LMNA (1.00) SERPINA6SHBGLMNANR3C1CYP2C19
Hydroxyprogesterone SCHEMBL18261234 0.82 LMNA (1.00) SERPINA6SHBGLMNANR3C1CYP2C19
Hydroxyprogesterone SCHEMBL24287585 0.82 LMNA (1.00) SERPINA6SHBGLMNANR3C1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4547 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250144021-A1 GEL FORMULATIONS FOR LOCAL DRUG RELEASE TECHNICAL UNIVERSITY OF DENMARK (DK) 2025-05-08 US claimed
US-12274681-B2 Compositions and methods for reducing skin fat PURDUE RESEARCH FOUNDATION (US) 2025-04-15 US claimed
WO-2025076059-A1 ROCAGLATE DERIVATIVES AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2025-04-10 WO claimed
EP-3943073-B1 BIODEGRADABLE POLYMER MICROPARTICLE CONTAINING STEROID-BASED DRUG AND PREPARATION METHOD THEREFOR REGENBIOTECH INC (KR) 2025-03-26 EP claimed
US-RE50218-E1 Non-steroidal anti-inflammatory ophthalmic compositions SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2024-11-26 US claimed
US-20240050632-A1 SELF-EXPANDING DEVICES AND METHODS THEREFOR INTERSECT ENT, INC 2024-02-15 US claimed
US-20240041935-A1 PREVENTION AND TREATMENT OF REPRODUCTIVE FAILURE BY REGENERATIVE CELLS AND ADJUVANTS CREATIVE MEDICAL TECHNOLOGIES, INC. (US) 2024-02-08 US claimed
US-11826494-B2 Self-expanding devices and methods therefor INTERSECT ENT, INC. (US) 2023-11-28 US claimed
EP-4013420-B1 METHOD OF BLOCKING OR AMELIORATING CYTOKINE RELEASE SYNDROME RIGEL PHARMACEUTICALS INC (US) 2023-11-01 EP claimed
US-20230270701-A1 COMPOSITIONS AND METHODS FOR REDUCING SKIN FAT PURDUE RESEARCH FOUNDATION 2023-08-31 US claimed
EP-0792371-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-09-03 EP claimed
EP-0786999-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-08-06 EP claimed
EP-0136011-B1 A method of hormonal treatment of peri-menopausal, menopausal and post-menopausal disorders and multi-preparation pack therefor PRE JAY HOLDINGS LTD (CA) 1997-01-22 EP claimed
US-5543417-A 5 Alpha-reductase inhibitor and at least one of an antibacterial agent, a keratolytic agent or an anti-inflammatory agent MERCK & CO., INC. (US) 1996-08-06 US claimed
WO-1996012487-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
WO-1996012817-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
EP-0496520-A1 Novel bone acting agents MERCK & CO. INC. (US) 1992-07-29 EP claimed
US-4346709-A Drug delivery devices comprising erodible polymer and erosion rate modifier ALZA CORPORATION (US) 1982-08-31 US claimed
US-4016270-A Method for treating dysmenorrhea with a uterine therapeutic system ALZA CORPORATION (US) 1977-04-05 US claimed
US-4014988-A Method for treating hypermenorrhea with uterine therapeutic system ALZA CORPORATION (US) 1977-03-29 US claimed