Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 6/20 | 0.41 |
| ▸ | AR | P10275 | 12/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2119470 | 1.00 | RET (0.41) | RETARPRKAA2 | |
| SCHEMBL2617867 | 1.00 | RET (0.41) | RETARPRKAA2 | |
| SCHEMBL2617866 | 0.91 | AR (0.46) | RETARPRKAA2 | |
| SCHEMBL2617865 | 0.91 | SMN1; SMN2 (0.43) | RETARPRKAA2 | |
| SCHEMBL2119282 | 0.91 | SMN1; SMN2 (0.43) | RETARPRKAA2 | |
| SCHEMBL2119410 | 0.91 | AR (0.46) | RETARPRKAA2 | |
| SCHEMBL2617802 | 0.91 | SMN1; SMN2 (0.43) | RETARPRKAA2 | |
| SCHEMBL2617778 | 0.91 | PRKAA2 (0.42) | RETARPRKAA2 | |
| SCHEMBL2617835 | 0.91 | PRKAA2 (0.42) | RETARPRKAA2 | |
| SCHEMBL2120388 | 0.91 | PRKAA2 (0.42) | RETARPRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507474-B2 | Anthelmintic agents and their use | INTERVET INTERNATIONAL B.V. (NL) | 2013-08-13 | — | — | US | disclosed |
| US-20120094981-A1 | ANTHELMINTIC AGENTS AND THEIR USE | INTERVET INTERNATIONAL B.V. (NL) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094981-A1 | ANTHELMINTIC AGENTS AND THEIR USE | ABCB11, ACHE, CMA1 | RET 4682/4885AR 4346/4885PRKAA2 4495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.