Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 15/20 | 0.78 |
| ▸ | HTR1B | P28222 | 15/20 | 0.78 |
| ▸ | HTR1A | P08908 | 11/20 | 0.78 |
| ▸ | HTR2A | P28223 | 5/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.78 |
| ▸ | HTR1F | P30939 | 2/20 | 0.60 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811321 | 0.89 | HTR1D (0.75) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL8091337 | 0.89 | HTR1D (0.75) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL7811586 | 0.89 | HTR1D (0.75) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL8091339 | 0.89 | HTR1D (0.75) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL5528416 | 0.89 | HTR1D (0.75) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL8040765 | 0.88 | HTR1D (0.81) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL8040759 | 0.88 | HTR1D (0.81) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| Zolmitriptan SCHEMBL40595 | 0.88 | HTR1D (1.00) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| Zolmitriptan SCHEMBL33336 | 0.88 | HTR1D (1.00) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| Zolmitriptan SCHEMBL14861150 | 0.88 | HTR1D (1.00) | HTR1DHTR1BHTR1AHTR2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2444072-A2 | Non-mucoadhesive film dosage forms | Labtec GmbH (DE) | 2012-04-25 | — | — | EP | disclosed |
| EP-2248519-A2 | Non-mucoadhesive film dosage forms | Labtec GmbH (DE) | 2010-11-10 | — | — | EP | disclosed |
| WO-2008040534-A2 | NON-MUCOADHESIVE FILM DOSAGE FORMS | LABTEC Gesellschaft für technologische Forschung und Entwicklung mbH (DE) | 2008-04-10 | — | — | WO | disclosed |
| WO-2007127207-A2 | FIXED COMBINATION DOSAGE FORMS FOR THE TREATMENT OF MIGRAINE | PROETHIC PHARMACEUTICALS, INC. (US) | 2007-11-08 | — | — | WO | disclosed |