Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12859040 | 0.93 | ELANE (0.78) | ELANECYP3A4CYP2C9 | |
| SCHEMBL2618008 | 0.92 | ELANE (0.79) | ELANECYP3A4CYP2C9 | |
| SCHEMBL2618007 | 0.92 | ELANE (0.79) | ELANECYP3A4CYP2C9 | |
| SCHEMBL12859332 | 0.92 | ELANE (0.68) | ELANECYP3A4CYP2C9 | |
| SCHEMBL2617956 | 0.92 | ELANE (0.68) | ELANECYP3A4CYP2C9 | |
| SCHEMBL12859033 | 0.92 | ELANE (0.68) | ELANECYP3A4CYP2C9 | |
| SCHEMBL12859279 | 0.91 | ELANE (0.70) | ELANECYP3A4CYP2C9 | |
| SCHEMBL2617979 | 0.90 | ELANE (0.66) | ELANECYP3A4CYP2C9 | |
| SCHEMBL12859339 | 0.88 | ELANE (0.64) | ELANECYP3A4CYP2C9 | |
| SCHEMBL12859330 | 0.88 | ELANE (0.66) | ELANECYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8691817-B2 | Sulfonic amide and sulfoximine-substituted diaryl-dihydropyrimidinones and usage thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-04-08 | — | — | US | disclosed |
| US-20120094968-A1 | SULFONIC AMIDE AND SULFOXIMINE-SUBSTTTUTED DIARYL-DIHYDROPYRIMIDINONES AND USAGE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094968-A1 | SULFONIC AMIDE AND SULFOXIMINE-SUBSTTTUTED DIARYL-DIHYDROPYRIMIDINONES AND USAGE THEREOF | STS, SQOR, TST | ELANE 2343/4885CYP3A4 1774/4885CYP2C9 2026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.