Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | RXRB | P28702 | 1/20 | 0.54 |
| ▸ | RXRG | P48443 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 9/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14328002 | 0.84 | RXRA (0.57) | RXRARXRBRXRGS1PR1CTSS | |
| SCHEMBL25735783 | 0.83 | S1PR1 (0.45) | S1PR1IDO1PTPN1 | |
| SCHEMBL2415055 | 0.83 | RXRA (0.59) | RXRARXRBRXRGS1PR1CTSS | |
| SCHEMBL30488261 | 0.83 | RXRA (0.59) | RXRARXRBRXRGS1PR1CTSS | |
| SCHEMBL2019451 | 0.83 | RXRA (0.59) | RXRARXRBRXRGS1PR1CTSS | |
| SCHEMBL932902 | 0.83 | RXRA (0.56) | RXRARXRBRXRGS1PR1CTSS | |
| SCHEMBL247961 | 0.83 | CSNK2A1 (0.59) | RXRARXRBRXRGS1PR1CTSS | |
| SCHEMBL22310791 | 0.77 | CSNK2A1 (0.44) | P2RX3CSNK2A1MEN1LMNAKMT2A | |
| SCHEMBL27821346 | 0.76 | RXRA (0.48) | RXRARXRBRXRGCTSSCTSK | |
| SCHEMBL26291514 | 0.76 | RXRA (0.46) | RXRARXRBRXRGS1PR1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107563-A1 | CARBOXYLIC ACID CONTAINING INDANYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | CELGENE CORPORATION (US) | 2023-06-15 | — | — | WO | disclosed |