Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.59 |
| ▸ | RXRB | P28702 | 1/20 | 0.59 |
| ▸ | RXRG | P48443 | 1/20 | 0.59 |
| ▸ | S1PR1 | P21453 | 11/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2019451 | 1.00 | RXRA (0.59) | RXRARXRBRXRGS1PR1AR | |
| SCHEMBL2328507 | 0.88 | RXRA (0.47) | RXRARXRBRXRGS1PR1AR | |
| SCHEMBL14328002 | 0.85 | RXRA (0.57) | RXRARXRBRXRGS1PR1CTSS | |
| SCHEMBL26291337 | 0.85 | RXRA (0.44) | RXRARXRBRXRGS1PR1AR | |
| SCHEMBL932902 | 0.84 | RXRA (0.56) | RXRARXRBRXRGS1PR1CTSS | |
| SCHEMBL2415055 | 0.84 | RXRA (0.59) | RXRARXRBRXRGS1PR1CTSS | |
| SCHEMBL247961 | 0.84 | CSNK2A1 (0.59) | RXRARXRBRXRGS1PR1CTSS | |
| SCHEMBL26179843 | 0.83 | RXRA (0.54) | RXRARXRBRXRGS1PR1CTSS | |
| SCHEMBL10088920 | 0.83 | RXRA (0.42) | RXRARXRBRXRGS1PR1AR | |
| SCHEMBL1437536 | 0.81 | S1PR1 (0.58) | RXRARXRBRXRGS1PR1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444697-A1 | CARBOXYLIC ACID CONTAINING INDANYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | CELGENE CORPORATION (US) | 2024-10-16 | — | — | EP | disclosed |
| CN-118632834-A | Indanyl compounds containing carboxylic acids for the treatment of neurodegenerative diseases | 细胞基因公司 | 2024-09-10 | — | — | CN | disclosed |
| WO-2023107563-A1 | CARBOXYLIC ACID CONTAINING INDANYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | CELGENE CORPORATION (US) | 2023-06-15 | — | — | WO | disclosed |