Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 2/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1413179 | 0.91 | APEX1 (0.64) | APEX1CASP6NT5ECASRPRMT1 | |
| SCHEMBL29516436 | 0.91 | APEX1 (0.64) | APEX1CASP6NT5ECASRPRMT1 | |
| SCHEMBL29575995 | 0.91 | APEX1 (0.64) | APEX1CASP6NT5ECASRPRMT1 | |
| SCHEMBL5147103 | 0.90 | APEX1 (0.63) | APEX1CASP6NT5ECASRPRMT1 | |
| SCHEMBL8010537 | 0.90 | APEX1 (0.63) | APEX1CASP6NT5ECASRPRMT1 | |
| Phenol SCHEMBL11600632 | 0.83 | APEX1 (0.69) | APEX1CASP6NT5ECASRPRMT1 | |
| SCHEMBL11773973 | 0.81 | CASP6 (0.59) | APEX1CASP6NT5ECASRPRMT1 | |
| SCHEMBL13534219 | 0.80 | NT5E (0.61) | APEX1CASP6NT5EPRMT1PTPN1 | |
| SCHEMBL1807848 | 0.80 | CASP6 (0.50) | APEX1CASP6NT5ECASRPRMT1 | |
| SCHEMBL10901189 | 0.79 | APEX1 (0.68) | APEX1CASP6NT5ECASRPRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8664371-B2 | Rinsable dyes and methods for their preparation | Spectra Colors Corp. (US) | 2014-03-04 | — | — | US | disclosed |
| US-20120101264-A1 | Rinsable dyes and methods for their preparation | Spectra Colors Corp. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101264-A1 | Rinsable dyes and methods for their preparation | ARSA, HNRNPUL1, ALKBH1 | APEX1 1266/4885CASP6 929/4885NT5E 2151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.