SCHEMBL26181538

SCHEMBL26181538

N#Cc1cc2cnc(N)nc2c(N2CCCCC2)n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 3/20 0.41
CHUK O15111 1/20 0.40
CTSK P43235 2/20 0.39
KDM4E B2RXH2 5/20 0.38
ALDH1A1 P00352 5/20 0.38
HPGD P15428 5/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
HSD17B10 Q99714 4/20 0.38
RAB9A P51151 3/20 0.38
MAPT P10636 3/20 0.38
CASP1 P29466 3/20 0.38
POLB P06746 2/20 0.38
BLM P54132 2/20 0.38
CASP7 P55210 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
RECQL P46063 2/20 0.38
APAF1 O14727 1/20 0.38
PLA2G1B P04054 1/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25228181 0.81 MEN1 (0.40) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL25275249 0.79 KDM4E (0.36) NOS1KDM4EALDH1A1HPGDMEN1
SCHEMBL25230226 0.77 CTSK (0.36) CHUKCTSKKDM4EALDH1A1HPGD
SCHEMBL25275355 0.77 CTSK (0.36) CHUKCTSKKDM4EALDH1A1HPGD
SCHEMBL26181386 0.77 ALDH1A1 (0.41) CTSKKDM4EALDH1A1HPGDMEN1
SCHEMBL26179945 0.75 CDC7 (0.40) KDM4EMAPTGAAADORA2AHTT
SCHEMBL13788691 0.69 ADORA2A (0.46) CHUKCTSKKDM4EALDH1A1HPGD
SCHEMBL25229118 0.69 MAPK8 (0.37) CTSKKDM4EALDH1A1HPGDHSD17B10
SCHEMBL13999707 0.68 LRRK2 (0.43) CHUKCTSKKDM4EALDH1A1HPGD
SCHEMBL26180491 0.67 ABL1 (0.37) KDM4EALDH1A1HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023109959-A1 CDK9 INHIBITOR AND USE THEREOF 药捷安康(南京)科技股份有限公司 2023-06-22 WO disclosed