Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.65 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | NSD2 | O96028 | 2/20 | 0.48 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30610015 | 1.00 | ELANE (0.65) | ELANEMAOAMAOBPOLBLCK | |
| Tectoquinone SCHEMBL28235019 | 0.90 | ELANE (0.57) | ELANEMAOAMAOBPOLBLCK | |
| SCHEMBL6906411 | 0.83 | S100A4 (0.61) | MAOAMAOBNSD2MAPTMAPK1 | |
| SCHEMBL31375388 | 0.83 | S100A4 (0.61) | MAOAMAOBNSD2MAPTMAPK1 | |
| SCHEMBL6899117 | 0.83 | S100A4 (0.61) | MAOAMAOBNSD2MAPTMAPK1 | |
| SCHEMBL6761959 | 0.83 | ELANE (0.69) | ELANEMAOAMAOBPOLBLCK | |
| Anthraquinone SCHEMBL5172785 | 0.82 | ADORA2A (0.57) | MAOAMAOBNSD2MAPTMAPK1 | |
| SCHEMBL29401197 | 0.82 | ADORA2A (0.57) | MAOAMAOBNSD2MAPTMAPK1 | |
| SCHEMBL36815 | 0.82 | ADORA2A (0.57) | MAOAMAOBNSD2MAPTMAPK1 | |
| Anthraquinone SCHEMBL28163374 | 0.81 | S100A4 (0.65) | ELANEMAOAMAOBNSD2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023199238-A1 | NOVEL COMPOUNDS TO TREAT CYTOKINE RELATED DISORDERS | ZYDUS LIFESCIENCES LIMITED (IN) | 2023-10-19 | — | — | WO | disclosed |
| WO-2023199238-A1 | NOVEL COMPOUNDS TO TREAT CYTOKINE RELATED DISORDERS | ZYDUS LIFESCIENCES LIMITED (IN) | 2023-10-19 | — | — | WO | disclosed |