SCHEMBL26187791

C[C@H]1[C@H](OCCOCCOCCNC(=O)CCOCC(COCCC(=O)NCCOCCOCCO[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2C)(COCCC(=O)NCCOCCOCCO[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2C)NC(=O)CNC(=O)COCCOCCOCCNc2ccc([N+](=O)[O-])cc2[N+](=O)[O-])O[C@H](CO)[C@H](O)[C@@H]1O

nearest known ligand 0.44

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	ALDH1A1	P00352	2/20	0.38

▸	CYP1A2	P05177	1/20	0.38

▸	NFKB1	P19838	1/20	0.38

▸	THPO	P40225	1/20	0.38

▸	PMP22	Q01453	1/20	0.38

▸	MAPT	P10636	2/20	0.35

▸	KDM4E	B2RXH2	1/20	0.35

▸	KMT2A	Q03164	1/20	0.34

▸	FOLH1	Q04609	7/20	0.34

▸	DGAT1	O75907	5/20	0.33

▸	POLB	P06746	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL26187897	0.88	LGALS3 (0.36)	ALDH1A1CYP1A2NFKB1THPOPMP22
SCHEMBL30290805	0.84	KMT2A (0.48)	ALDH1A1MAPTKDM4EKMT2AFOLH1
SCHEMBL26187793	0.79	KMT2A (0.44)	ALDH1A1MAPTKDM4EKMT2AFOLH1
SCHEMBL17480007	0.78	PYGB (0.36)	—
SCHEMBL26880449	0.77	MAPT (0.35)	ALDH1A1MAPTKDM4EKMT2AFOLH1
SCHEMBL15681564	0.76	MDK (0.37)	ALDH1A1KMT2A
SCHEMBL19679966	0.76	MAPK1 (0.36)	KMT2A
SCHEMBL26873026	0.76	MAPK1 (0.36)	—
SCHEMBL25656639	0.76	MAPK1 (0.36)	KMT2A
SCHEMBL17849329	0.76	MAPK1 (0.36)	KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230271994-A1	MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS	UNIV YALE (US)	2023-08-31	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20230271994-A1	MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS	ASGR1, MSR1, LDLR	ALDH1A1 1363/4885CYP1A2 3142/4885NFKB1 2045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.