Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | SMYD3 | Q9H7B4 | 10/20 | 0.60 |
| ▸ | STAT1 | P42224 | 2/20 | 0.59 |
| ▸ | STAT3 | P40763 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22518513 | 0.83 | RAB9A (0.63) | RAB9ANPC1TSHRSMYD3STAT1 | |
| SCHEMBL13835610 | 0.80 | RAB9A (0.56) | RAB9ANPC1TSHRSMYD3STAT1 | |
| SCHEMBL11721317 | 0.80 | RAB9A (0.60) | RAB9ANPC1TSHRSMYD3STAT1 | |
| SCHEMBL11721595 | 0.80 | RAB9A (0.57) | RAB9ANPC1TSHRSMYD3STAT1 | |
| SCHEMBL28856869 | 0.80 | S1PR3 (0.58) | RAB9ANPC1TSHRSMYD3STAT1 | |
| SCHEMBL20305303 | 0.79 | SMN1; SMN2 (0.65) | RAB9ANPC1TSHRSMYD3STAT1 | |
| SCHEMBL19064412 | 0.79 | RAB9A (0.60) | RAB9ANPC1TSHRSMYD3STAT1 | |
| SCHEMBL13835269 | 0.79 | RAB9A (0.64) | RAB9ANPC1TSHRSMYD3STAT1 | |
| SCHEMBL841342 | 0.78 | S1PR3 (0.57) | RAB9ANPC1TSHRSMYD3STAT1 | |
| SCHEMBL23976629 | 0.78 | HIF1A (0.59) | RAB9ANPC1TSHRSMYD3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193604-B1 | SUBSTITUTED N-(PYRROLIDIN-3-YL)ISOXAZOLE-3-CARBOXAMIDE COMPOUNDS | EPIZYME INC (US) | 2021-06-16 | — | — | EP | disclosed |
| US-20200148650-A1 | ISOXAZOLE CARBOXAMIDE COMPOUNDS | Epizyme, Inc. | 2020-05-14 | — | — | US | disclosed |
| US-20120101031-A1 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101031-A1 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | TMPRSS15, PRSS1, SPINT2 | RAB9A 3337/4885NPC1 100/4885TSHR 4173/4885 |
| US-20200148650-A1 | ISOXAZOLE CARBOXAMIDE COMPOUNDS | SMYD3, SMYD2, SNRPD3 | RAB9A 705/4885NPC1 3842/4885TSHR 3513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.