Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18526530 | 0.86 | NOS3 (0.38) | NOS3NOS2 | |
| SCHEMBL24857964 | 0.76 | NOS3 (0.34) | NOS3NOS2 | |
| SCHEMBL24124442 | 0.70 | — | — | |
| SCHEMBL27984799 | 0.69 | ALDH1A1 (0.41) | NOS3NOS2 | |
| SCHEMBL25057474 | 0.68 | — | — | |
| SCHEMBL25057412 | 0.66 | — | — | |
| SCHEMBL30073071 | 0.65 | NOS3 (0.36) | NOS3NOS2 | |
| SCHEMBL27609812 | 0.64 | NOS3 (0.35) | NOS3NOS2 | |
| SCHEMBL25057543 | 0.64 | HTT (0.33) | — | |
| SCHEMBL18526520 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3621624-B1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME LLC (US) | 2023-08-30 | — | — | EP | disclosed |