Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30177045 | 1.00 | IDO1 (0.36) | IDO1ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL26196439 | 0.77 | ALDH1A1 (0.39) | ALDH1A1LMNASMN1; SMN2MAPTNPC1 | |
| SCHEMBL27433891 | 0.77 | GLA (0.37) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL15431214 | 0.76 | IDO1 (0.44) | IDO1ALDH1A1LMNAMAPTPOLB | |
| SCHEMBL30177024 | 0.76 | PIK3CD (0.42) | IDO1ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL28983677 | 0.76 | PIK3CD (0.42) | IDO1ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL1772484 | 0.74 | CASP3 (0.51) | IDO1ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL4249584 | 0.73 | IDO1 (0.42) | IDO1ALDH1A1LMNAMAPTPOLB | |
| SCHEMBL1368267 | 0.73 | IDO1 (0.46) | IDO1ALDH1A1LMNAMAPTPOLB | |
| SCHEMBL23974673 | 0.73 | IDO1 (0.44) | IDO1ALDH1A1LMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217965-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS | PLEXXIKON INC. | 2024-07-04 | — | — | US | disclosed |
| US-11739088-B2 | Synthesis of heterocyclic compounds | PLEXXIKON INC. (US) | 2023-08-29 | — | — | US | disclosed |
| CN-115605460-A | Synthesis of heterocyclic compounds | 普莱希科公司（US） | 2023-01-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240217965-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS | CBR3, CBR1, CCNL2 | IDO1 2069/4885ALDH1A1 2145/4885LMNA 2512/4885 |
| US-11739088-B2 | Synthesis of heterocyclic compounds | CBR3, CBR1, CCNL2 | IDO1 2069/4885ALDH1A1 2145/4885LMNA 2512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.