Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | FASN | P49327 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30276525 | 0.98 | DPP4 (0.37) | DPP4ALDH1A1HTTNPSR1HTR1A | |
| SCHEMBL18849753 | 0.84 | MEN1 (0.44) | DPP4ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL2171890 | 0.82 | CYP1A2 (0.50) | DPP4HTTHTR1APOLBCYP1A2 | |
| SCHEMBL7926325 | 0.81 | DPP4 (0.44) | DPP4ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL25530292 | 0.80 | HRH3 (0.38) | DPP4MEN1KMT2AKCNH2POLB | |
| Hydrochloric Acid SCHEMBL15742309 | 0.80 | CYP1A2 (0.48) | DPP4HTTNPSR1HTR1APOLB | |
| SCHEMBL12519995 | 0.79 | ALDH1A1 (0.44) | DPP4ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL6258296 | 0.78 | KDM4E (0.46) | DPP4ALDH1A1KMT2APOLBCYP1A2 | |
| SCHEMBL422638 | 0.77 | — | — | |
| SCHEMBL572569 | 0.77 | ALDH1A1 (0.45) | ALDH1A1HTTNPSR1HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129963-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2023-07-06 | — | — | WO | disclosed |