Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3760781 | 0.96 | LMNA (0.53) | LMNATSHRALDH1A1THRBHTT | |
| SCHEMBL17908741 | 0.89 | LMNA (0.56) | LMNATSHRALDH1A1THRBHTT | |
| SCHEMBL17909643 | 0.89 | LMNA (0.56) | LMNATSHRALDH1A1THRBHTT | |
| SCHEMBL17909423 | 0.89 | LMNA (0.56) | LMNATSHRALDH1A1THRBHTT | |
| SCHEMBL10404989 | 0.86 | LMNA (0.57) | LMNATSHRALDH1A1HTTMAPT | |
| SCHEMBL20210501 | 0.84 | LMNA (0.60) | LMNATSHRALDH1A1MAPTALOX15 | |
| SCHEMBL26199851 | 0.84 | LMNA (0.46) | LMNATSHRALDH1A1HTTMAPT | |
| SCHEMBL27842524 | 0.84 | LMNA (0.43) | LMNATSHRALDH1A1HTTMAPT | |
| SCHEMBL27643860 | 0.82 | LMNA (0.63) | LMNATSHRALDH1A1MAPTHSD17B10 | |
| SCHEMBL26199693 | 0.82 | TDP1 (0.45) | LMNATSHRALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3621624-B1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME LLC (US) | 2023-08-30 | — | — | EP | disclosed |