Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.50 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.50 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TOP1 | P11387 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12853982 | 0.94 | FGFR1 (0.49) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL895721 | 0.94 | FGFR1 (0.49) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL13684920 | 0.91 | KDM4E (0.50) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL4349595 | 0.86 | FABP3 (0.43) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL11099506 | 0.86 | APP (0.50) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL13685138 | 0.84 | FGFR1 (0.46) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL355567 | 0.84 | CA1 (0.57) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL294721 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KDM4ECA1CA2CA7 | |
| SCHEMBL30136447 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KDM4ECA1CA2CA7 | |
| Biphenyl SCHEMBL6280726 | 0.84 | FGFR1 (0.43) | ALDH1A1MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164679-A1 | PROCESSES FOR THE PREPARATION OF PHENYLTETRAHYDROFURAN COMPOUNDS | GENENTECH, INC. (US) | 2023-08-31 | — | — | WO | disclosed |