SCHEMBL355567

SCHEMBL355567

COc1cccc(OC)c1-c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.57
CA2 P00918 4/20 0.57
CA7 P43166 3/20 0.57
CA9 Q16790 3/20 0.57
CA12 O43570 2/20 0.57
CA14 Q9ULX7 2/20 0.57
CA4 P22748 1/20 0.57
FABP4 P15090 2/20 0.53
FABP3 P05413 1/20 0.53
FABP5 Q01469 1/20 0.53
HTR1A P08908 2/20 0.49
HTR7 P34969 2/20 0.49
PDE4A P27815 1/20 0.48
PDE4B Q07343 1/20 0.48
PDE4C Q08493 1/20 0.48
PDE4D Q08499 1/20 0.48
SYK P43405 1/20 0.47
ALDH1A1 P00352 6/20 0.46
TP53 P04637 3/20 0.46
TDP1 Q9NUW8 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28136778 0.98 CA1 (0.55) CA1CA2CA7CA9CA12
Benzene SCHEMBL28977457 0.98 CA1 (0.55) CA1CA2CA7CA9CA12
Phosphine SCHEMBL27891320 0.98 CA1 (0.55) CA1CA2CA7CA9CA12
Hydrochloric Acid SCHEMBL30310852 0.98 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL8592250 0.93 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL29217584 0.93 FABP4 (0.53) CA1CA2CA7CA9CA12
SCHEMBL28518857 0.89 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL13684920 0.89 KDM4E (0.50) CA1CA2CA7CA9CA12
SCHEMBL27963031 0.88 ALDH1A1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL9446206 0.87 SYK (0.50) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 657 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570632-B2 Indole derivatives and uses thereof for treating a cancer UNIVERSITE CLAUDE BERNARD LYON 1 (FR) 2026-03-10 US claimed
US-20260040755-A1 DIVALENT METAL COMPLEX, PREPARATION METHOD AND USE THEREOF, AND ORGANIC OPTOELECTRONIC DEVICE CHINA PETROLEUM & CHEM CORP (CN) 2026-02-05 US claimed
EP-4563584-A1 DIVALENT METAL COMPLEX, PREPARATION METHOD THEREFOR AND USE THEREOF, AND ORGANIC OPTOELECTRONIC DEVICE China Petroleum & Chemical Corporation (CN) 2025-06-04 EP claimed
CN-119191946-A Electrophilic cross-coupling method of aryl perfluoro butyl sulfonate and aryl bromide 南京工业大学 2024-12-27 CN claimed
CN-117384024-B Method for preparing aryl straight-chain carboxylic acid from oxalic acid 常州大学 2024-11-08 CN claimed
WO-2024199100-A1 PREPARATION METHOD FOR AXL INHIBITOR INTERMEDIATE 南京正大天晴制药有限公司 2024-10-03 WO claimed
US-20240326030-A1 PALLADIUM COMPLEX AND CATALYST EMBODIMENTS AND METHODS OF MAKING AND USING THE SAME UVIC INDUSTRY PARTNERSHIPS INC. (CA) 2024-10-03 US claimed
WO-2024199102-A1 METHOD FOR PREPARING AXL INHIBITOR 南京正大天晴制药有限公司 2024-10-03 WO claimed
EP-4175718-B1 INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER UNIV CLAUDE BERNARD LYON (FR) 2024-10-02 EP claimed
CN-118666745-A Preparation method of C2-site arylation or alkenylation quinoline compound 郑州大学 2024-09-20 CN claimed
US-20210147452-A1 TRIARYL PHOSPHINE LIGANDS, PREPARATION METHOD THEREFOR, AND USE IN CATALYSING COUPLING REACTIONS DONGGUAN STEPHEN CATALYST CO., LTD. (CN) 2021-05-20 US claimed
EP-3766891-A1 TRIARYL PHOSPHINE LIGANDS, PREPARATION METHOD THEREFOR, AND USE IN CATALYSING COUPLING REACTIONS Dongguan Stephen Catalyst Co., Ltd. (CN) 2021-01-20 EP claimed
WO-2019170163-A1 TRIARYL PHOSPHINE LIGANDS, PREPARATION METHOD THEREFOR, AND USE IN CATALYSING COUPLING REACTIONS 东莞市均成高新材料有限公司 2019-09-12 WO claimed
CN-107459535-A Polysubstituted quinoline coordinated iridium hybrid compound and preparation method and application thereof 南京工业大学 2017-12-12 CN claimed
US-8916663-B2 Production method of copolymer of allyl monomer containing polar group THE UNIVERSITY OF TOKYO (JP) 2014-12-23 US claimed
EP-2470575-B9 PRODUCTION METHOD OF COPOLYMER OF ALLYL MONOMER CONTAINING POLAR GROUP UNIV TOKYO (JP) 2014-01-15 EP claimed
EP-2470575-B1 PRODUCTION METHOD OF COPOLYMER OF ALLYL MONOMER CONTAINING POLAR GROUP UNIV TOKYO (JP) 2013-10-09 EP claimed
US-20120116036-A1 PRODUCTION METHOD OF COPOLYMER OF ALLYL MONOMER CONTAINING POLAR GROUP SHOWA DENKO K.K. (JP) 2012-05-10 US claimed
US-6420418-B1 INHIBITION AND PREVENTION OF LEUKOCYTE ADHESION; USED TO TREAT ADHESION-MEDIATED DISEASES SUCH AS ASTHMA, ALLERGIC RHINITIS, MULTIPLE SCLEROSIS; ATHEROSCLEROSIS, AND INFLAMMATORY BOWEL DISEASE MERCK & CO., INC. 2002-07-16 US claimed
WO-2000071572-A1 SUBSTITUTED BETA-ALANINE DERIVATIVES AS CELL ADHESION INHIBITORS MERCK & CO., INC. (US) 2000-11-30 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570632-B2 Indole derivatives and uses thereof for treating a cancer CKS2, CSNK2A3, CSNK1A1L CA1 476/4885CA2 274/4885CA7 139/4885
US-20260040755-A1 DIVALENT METAL COMPLEX, PREPARATION METHOD AND USE THEREOF, AND ORGANIC OPTOELECTRONIC DEVICE SCO2, TIMCC, TMCO1 CA1 564/4885CA2 162/4885CA7 247/4885
US-20240326030-A1 PALLADIUM COMPLEX AND CATALYST EMBODIMENTS AND METHODS OF MAKING AND USING THE SAME PDCD6IP, PDPK1, PDCD10 CA1 1318/4885CA2 1046/4885CA7 1476/4885
US-20210147452-A1 TRIARYL PHOSPHINE LIGANDS, PREPARATION METHOD THEREFOR, AND USE IN CATALYSING COUPLING REACTIONS WEE1, WEE2, NOTUM CA1 3819/4885CA2 3347/4885CA7 1267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.