SCHEMBL26200285

SCHEMBL26200285

COC(CCc1ccc2c(N)ncnn12)COC(=O)C(C)C

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ RIPK1 Q13546 7/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26241474 0.86 RIPK1 (0.34) RIPK1
SCHEMBL25722745 0.83 TNK2 (0.33) RIPK1
SCHEMBL18666942 0.83 RIPK1 (0.35) RIPK1
SCHEMBL24606291 0.81 ACVRL1 (0.36) RIPK1
SCHEMBL26241383 0.80 PIK3CD (0.32) —
SCHEMBL26949660 0.80 RIPK1 (0.34) RIPK1
SCHEMBL24057840 0.79 RIPK1 (0.36) RIPK1
SCHEMBL24736797 0.78 RIPK1 (0.34) RIPK1
SCHEMBL18666897 0.78 RIPK1 (0.34) RIPK1
SCHEMBL18667178 0.77 RIPK1 (0.35) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023167938-A1 COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS GILEAD SCIENCES, INC. (US) 2023-09-07 — — WO disclosed
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