SCHEMBL27718679

SCHEMBL27718679

C=CC(=O)O[SiH2]OC(C)=O

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
TSHR P16473 6/20 0.35
HPGD P15428 1/20 0.34
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
CYP3A4 P08684 2/20 0.33
HSD17B10 Q99714 1/20 0.33
KEAP1 Q14145 1/20 0.31
NFE2L2 Q16236 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL262019 0.87 TSHR (0.40) ALDH1A1TSHRHPGDTP53HIF1A
Propene SCHEMBL27618700 0.82 ALDH1A1 (0.38) ALDH1A1TSHRHSD17B10
Butadiene SCHEMBL17498997 0.82 ALDH1A1 (0.38) ALDH1A1TSHRHSD17B10
SCHEMBL13685616 0.80 ALDH1A1 (0.39) ALDH1A1TSHRHPGDTP53HIF1A
SCHEMBL203137 0.79
SCHEMBL28824143 0.78
SCHEMBL27805582 0.76 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10
Methane SCHEMBL205249 0.76 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10
SCHEMBL28752872 0.73
SCHEMBL1591632 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116196769-A Method for treating microporous membranes PPG工业俄亥俄公司 2023-06-02 CN disclosed
CN-112689532-B Method for treating microporous membranes PPG工业俄亥俄公司 2023-04-28 CN disclosed
CN-112689532-A Method for treating microporous membranes PPG工业俄亥俄公司 2021-04-20 CN disclosed
CN-101297008-A Compositions containing a silanol functional polymer and related hydrophilic coating films PPG IND OHIO INC (US) 2008-10-29 CN disclosed