Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 12/20 | 0.59 |
| ▸ | DRD2 | P14416 | 10/20 | 0.54 |
| ▸ | DRD3 | P35462 | 7/20 | 0.54 |
| ▸ | DRD5 | P21918 | 6/20 | 0.54 |
| ▸ | F3 | P13726 | 5/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26203173 | 1.00 | DRD1 (0.59) | DRD1DRD2DRD3DRD5F3 | |
| SCHEMBL26203165 | 1.00 | DRD1 (0.59) | DRD1DRD2DRD3DRD5F3 | |
| SCHEMBL30000441 | 0.92 | DRD1 (0.62) | DRD1DRD2DRD3DRD5F3 | |
| SCHEMBL909815 | 0.92 | DRD1 (0.62) | DRD1DRD2DRD3DRD5F3 | |
| SCHEMBL26203168 | 0.90 | DRD1 (0.58) | DRD1DRD2DRD3DRD5F3 | |
| SCHEMBL910897 | 0.90 | DRD1 (0.58) | DRD1DRD2DRD3DRD5F3 | |
| SCHEMBL29405499 | 0.90 | DRD1 (0.58) | DRD1DRD2DRD3DRD5F3 | |
| SCHEMBL26203178 | 0.90 | DRD1 (0.58) | DRD1DRD2DRD3DRD5F3 | |
| SCHEMBL910354 | 0.89 | DRD1 (0.56) | DRD1DRD2DRD3DRD5F3 | |
| SCHEMBL30000006 | 0.89 | DRD1 (0.56) | DRD1DRD2DRD3DRD5F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279002-A1 | Polymorphs of Crystalline Forms of 3,10-dimethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinolin-9-yl 3-fluorobenzenesulfonate and Salts Thereof | CVI PHARMACEUTICALS LIMITED (KY) | 2023-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230279002-A1 | Polymorphs of Crystalline Forms of 3,10-dimethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinolin-9-yl 3-fluorobenzenesulfonate and Salts Thereof | GYS2, APOB, LSS | DRD1 4616/4885DRD2 4531/4885DRD3 3663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.