Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 13/20 | 0.62 |
| ▸ | PLAU | P00749 | 5/20 | 0.62 |
| ▸ | F2 | P00734 | 4/20 | 0.62 |
| ▸ | HTR3A | P46098 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17176463 | 0.83 | HTR3A (0.54) | ELANEPLAUF2HTR3AKDM4E | |
| SCHEMBL15557582 | 0.83 | HTR3A (0.54) | ELANEPLAUF2HTR3AHIF1A | |
| SCHEMBL9400073 | 0.82 | ELANE (0.52) | ELANEPLAUF2KDM4EALDH1A1 | |
| SCHEMBL19068173 | 0.79 | HTR3A (0.51) | ELANEPLAUF2HTR3AKMT2A | |
| SCHEMBL17170584 | 0.79 | HTR3A (0.54) | ELANEPLAUF2HTR3AKDM4E | |
| SCHEMBL2432444 | 0.79 | ELANE (0.74) | ELANEPLAUF2 | |
| SCHEMBL31302274 | 0.78 | KDM4E (0.66) | ELANEPLAUF2HTR3AKDM4E | |
| SCHEMBL1563104 | 0.78 | KDM4E (0.66) | ELANEPLAUF2HTR3AKDM4E | |
| SCHEMBL4476722 | 0.78 | ELANE (0.72) | ELANEPLAUF2 | |
| SCHEMBL1079201 | 0.77 | ELANE (0.62) | ELANEPLAUF2KDM4ENR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230278998-A1 | Compound containing structure of a five-membered heteroaromatic ring, pharmaceutical compositions thereof and applications thereof | 280 BIO, INC. (US) | 2023-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230278998-A1 | Compound containing structure of a five-membered heteroaromatic ring, pharmaceutical compositions thereof and applications thereof | PARG, CYP3A5, CYP11B1 | ELANE 2076/4885PLAU 1238/4885F2 915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.