Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26206369 | 0.90 | FFAR4 (0.39) | ALDH1A1PPARG | |
| SCHEMBL22526088 | 0.82 | AAK1 (0.39) | MEN1ALDH1A1KMT2AMAPTCNR2 | |
| SCHEMBL26206102 | 0.82 | MAPT (0.39) | MEN1ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL26206109 | 0.81 | HDAC1 (0.48) | CNR2PPARGPPARAMTNR1A | |
| SCHEMBL26206104 | 0.80 | F2 (0.38) | MAPTCNR2ADRB2ADRB1 | |
| SCHEMBL26206114 | 0.80 | HDAC1 (0.46) | CNR2PPARGPPARAMTNR1A | |
| SCHEMBL26206147 | 0.80 | MAPT (0.35) | MEN1ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL26205940 | 0.79 | ACACB (0.36) | KMT2AMAPTL3MBTL1ADRB2ADRB1 | |
| SCHEMBL25123368 | 0.79 | GPR88 (0.39) | MEN1ALDH1A1KMT2ACNR2L3MBTL1 | |
| SCHEMBL22526884 | 0.79 | S1PR4 (0.38) | CNR2L3MBTL1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | STAT4, STAT1, STAT3 | MEN1 3280/4885ALDH1A1 2465/4885KMT2A 737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.