SCHEMBL26206369

SCHEMBL26206369

C[C@@H](CCC(N)=O)COc1ccc(Cl)c(CCCCCC(=O)O)c1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ FFAR4 Q5NUL3 2/20 0.39
▸ FFAR1 O14842 1/20 0.39
▸ FOS P01100 2/20 0.38
▸ JUN P05412 2/20 0.38
▸ F13A1 P00488 3/20 0.37
▸ PLA2G2A P14555 1/20 0.37
▸ CSF3R Q99062 1/20 0.37
▸ TBXA2R P21731 1/20 0.36
▸ PTGER1 P34995 1/20 0.36
▸ PTGFR P43088 1/20 0.36
▸ PTGER3 P43115 1/20 0.36
▸ PTGER2 P43116 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ TSHR P16473 1/20 0.36
▸ MCL1 Q07820 1/20 0.36
▸ PPARG P37231 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26206096 0.90 MEN1 (0.38) ALDH1A1PPARG
SCHEMBL26206478 0.88 FOS (0.38) FOSJUNF13A1PLA2G2ACSF3R
SCHEMBL26206483 0.87 FFAR4 (0.39) FFAR4FFAR1FOSJUNF13A1
SCHEMBL26206459 0.82 FFAR1 (0.47) FFAR1
SCHEMBL22525554 0.81 AAK1 (0.41) FFAR4FFAR1PLA2G2ATBXA2RPTGER1
SCHEMBL30169427 0.81 AAK1 (0.41) FFAR4FFAR1PLA2G2ATBXA2RPTGER1
SCHEMBL26206371 0.81 S1PR1 (0.39) FFAR4FFAR1PPARG
SCHEMBL25123368 0.81 GPR88 (0.39) KDM4EALDH1A1TSHR
SCHEMBL26206374 0.81 PPARA (0.51) FFAR1FOSJUNPLA2G2ACSF3R
SCHEMBL26206373 0.80 TBXA2R (0.37) FFAR4CSF3RTBXA2RPTGER1PTGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11746120-B2 Stat degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2023-09-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11746120-B2 Stat degraders and uses thereof STAT4, STAT1, STAT3 FFAR4 3503/4885FFAR1 4114/4885FOS 3232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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