Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 6/20 | 0.36 |
| ▸ | PPARD | Q03181 | 6/20 | 0.36 |
| ▸ | PPARA | Q07869 | 6/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26206356 | 1.00 | ALDH1A1 (0.44) | ALDH1A1PLA2G2CTSHRLMNANFKB1 | |
| SCHEMBL26206360 | 1.00 | ALDH1A1 (0.44) | ALDH1A1PLA2G2CTSHRLMNANFKB1 | |
| SCHEMBL26205615 | 0.88 | PAOX (0.39) | PLA2G2CPMP22EPHX2KMT2ATLR2 | |
| SCHEMBL26205613 | 0.82 | CYP1A2 (0.42) | ALDH1A1TSHRLMNAEPHX2KMT2A | |
| SCHEMBL26205612 | 0.82 | CYP1A2 (0.42) | ALDH1A1TSHRLMNAEPHX2KMT2A | |
| SCHEMBL26206496 | 0.80 | PTPN7 (0.45) | ALDH1A1EPHX2KMT2AMAPTTDP1 | |
| SCHEMBL12355357 | 0.80 | ALDH1A1 (0.50) | ALDH1A1PLA2G2CTSHRLMNANFKB1 | |
| SCHEMBL26206347 | 0.79 | FFAR1 (0.47) | ALDH1A1LMNAFFAR1HSD17B10 | |
| SCHEMBL10596601 | 0.78 | ALDH1A1 (0.55) | ALDH1A1PLA2G2CTSHRLMNANFKB1 | |
| SCHEMBL2090432 | 0.78 | SPHK1 (0.42) | ALDH1A1PLA2G2CKMT2AMAPTTLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | STAT4, STAT1, STAT3 | ALDH1A1 2465/4885PLA2G2C 1935/4885TSHR 1768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.