Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26205612 | 1.00 | CYP1A2 (0.42) | CYP1A2MAPTALDH1A1TDP1ALOX15 | |
| SCHEMBL26206360 | 0.82 | ALDH1A1 (0.44) | MAPTALDH1A1TDP1ALOX15KMT2A | |
| SCHEMBL26206355 | 0.82 | ALDH1A1 (0.44) | MAPTALDH1A1TDP1ALOX15KMT2A | |
| SCHEMBL26206356 | 0.82 | ALDH1A1 (0.44) | MAPTALDH1A1TDP1ALOX15KMT2A | |
| SCHEMBL26205615 | 0.82 | PAOX (0.39) | CYP1A2ALOX15KMT2ACYP3A4EPHX2 | |
| SCHEMBL10596343 | 0.81 | MAPT (0.49) | CYP1A2MAPTALDH1A1TDP1ALOX15 | |
| SCHEMBL7046932 | 0.78 | CYP1A2 (0.65) | CYP1A2MAPTALDH1A1TDP1ALOX15 | |
| SCHEMBL31084215 | 0.78 | CYP1A2 (0.65) | CYP1A2MAPTALDH1A1TDP1ALOX15 | |
| SCHEMBL3043054 | 0.78 | CYP1A2 (0.65) | CYP1A2MAPTALDH1A1TDP1ALOX15 | |
| SCHEMBL31084214 | 0.78 | CYP1A2 (0.65) | CYP1A2MAPTALDH1A1TDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | STAT4, STAT1, STAT3 | CYP1A2 486/4885MAPT 3167/4885ALDH1A1 2465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.