SCHEMBL26206459

SCHEMBL26206459

C[C@@H](CCC(N)=O)COc1ccc(CCCCCC(=O)O)cc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ FFAR1 O14842 2/20 0.47
▸ MAPT P10636 1/20 0.46
▸ RXFP1 Q9HBX9 1/20 0.46
▸ S1PR1 P21453 7/20 0.44
▸ S1PR3 Q99500 3/20 0.44
▸ S1PR2 O95136 2/20 0.44
▸ S1PR5 Q9H228 3/20 0.44
▸ S1PR4 O95977 2/20 0.44
▸ CYSLTR2 Q9NS75 1/20 0.43
▸ CYSLTR1 Q9Y271 1/20 0.43
▸ LTB4R Q15722 1/20 0.43
▸ LMNA P02545 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ NR1H4 Q96RI1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26206414 0.90 LMNA (0.54) FFAR1LMNAL3MBTL1
SCHEMBL22525650 0.87 S1PR1 (0.44) MAPTS1PR1S1PR3S1PR2S1PR5
SCHEMBL26206374 0.86 PPARA (0.51) FFAR1MAPTRXFP1CYSLTR2CYSLTR1
SCHEMBL26206480 0.85 FFAR4 (0.39) FFAR1MAPTRXFP1S1PR1S1PR3
SCHEMBL26206322 0.84 MAPT (0.43) MAPTRXFP1S1PR1S1PR3S1PR2
SCHEMBL26206388 0.83 MAPT (0.50) FFAR1MAPTRXFP1S1PR1S1PR3
SCHEMBL26206373 0.83 TBXA2R (0.37) MAPTRXFP1S1PR1LTB4R
SCHEMBL26206478 0.83 FOS (0.38) LTB4R
SCHEMBL26206484 0.83 FFAR4 (0.37) MAPTRXFP1S1PR1S1PR3S1PR2
SCHEMBL26206481 0.83 TSHR (0.44) FFAR1MAPTRXFP1S1PR1S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11746120-B2 Stat degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2023-09-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11746120-B2 Stat degraders and uses thereof STAT4, STAT1, STAT3 FFAR1 4114/4885MAPT 3167/4885RXFP1 2746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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