SCHEMBL2620733

SCHEMBL2620733

C(#Cc1ccc2c(c1)c1cc(C#Cc3ccccc3)ccc1c1occc21)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 6/20 0.54
APP P05067 1/20 0.41
MAPT P10636 1/20 0.38
IP6K1 Q92551 1/20 0.38
IP6K3 Q96PC2 1/20 0.38
IP6K2 Q9UHH9 1/20 0.38
ASIC3 Q9UHC3 4/20 0.37
HNF4A P41235 1/20 0.37
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1290051 0.72 MAOA (0.41) MAPTRAB9ACA1CA9MEN1
SCHEMBL29383148 0.72 MAOA (0.41) MAPTRAB9ACA1CA9MEN1
SCHEMBL19386145 0.70 MAOA (0.39) MAPTRAB9ACA1CA9MEN1
SCHEMBL29787236 0.70 APP (0.52) GRM5APPMAPTIP6K1IP6K3
SCHEMBL19683509 0.70 MAOA (0.42) MAPTRAB9ACA1CA9MEN1
SCHEMBL10300103 0.68 GRM5 (0.57) GRM5APPMAPTASIC3HNF4A
SCHEMBL15071003 0.68 APP (0.50) GRM5APPMAPTIP6K1IP6K3
SCHEMBL13330692 0.68 IP6K1 (0.46) GRM5APPMAPTIP6K1IP6K3
SCHEMBL19683502 0.68 MAOA (0.41) CA1CA9MEN1KMT2A
SCHEMBL2114741 0.67 APP (0.92) GRM5APPMAPTHNF4ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9079872-B2 Phenanthro[9, 10-B]furans for electronic applications BASF SE (DE) 2015-07-14 US disclosed
US-9079872-B2 Phenanthro[9, 10-B]furans for electronic applications BASF SE (DE) 2015-07-14 US disclosed
EP-2625171-B1 PHENANTHRO[9,10-B]FURANS FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2014-07-30 EP disclosed
US-20120095222-A1 PHENANTHRO[9, 10-B]FURANS FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2012-04-19 US disclosed
US-20120095222-A1 PHENANTHRO[9, 10-B]FURANS FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2012-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120095222-A1 PHENANTHRO[9, 10-B]FURANS FOR ELECTRONIC APPLICATIONS P2RY10, P2RY11, P2RY12 GRM5 2984/4885APP 300/4885MAPT 2560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.