Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29383148 | 0.94 | MAOA (0.41) | MAOAMAOBFTOALDH1A1HPGD | |
| SCHEMBL1290051 | 0.94 | MAOA (0.41) | MAOAMAOBFTOALDH1A1HPGD | |
| SCHEMBL19386145 | 0.92 | MAOA (0.39) | MAOAMAOBFTOALDH1A1HPGD | |
| SCHEMBL19683509 | 0.91 | MAOA (0.42) | MAOAMAOBFTOALDH1A1HPGD | |
| SCHEMBL12270288 | 0.85 | ALDH1A1 (0.37) | MAOAMAOBFTOALDH1A1HPGD | |
| SCHEMBL19683512 | 0.83 | MAOA (0.34) | MAOAMAOBFTOALDH1A1HPGD | |
| SCHEMBL12270395 | 0.81 | MAOA (0.37) | MAOAMAOBFTOALDH1A1HPGD | |
| SCHEMBL19683516 | 0.81 | MAOA (0.33) | MAOAMAOBFTOALDH1A1HPGD | |
| Quinoxaline SCHEMBL29228383 | 0.78 | NCF1 (0.44) | ALDH1A1HPGDMEN1KMT2ACYP1A2 | |
| SCHEMBL19683285 | 0.77 | CYP1A1 (0.31) | MAOAMAOBALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017210072-A1 | ELECTROACTIVE COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2017-12-07 | — | — | WO | disclosed |