SCHEMBL2620743

SCHEMBL2620743

Cc1ccc(N2c3ccc(-n4c5ccccc5c5ccccc54)cc3[Si](c3ccccc3)(c3ccccc3)c3cc(-n4c5ccccc5c5ccccc54)ccc32)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.39
▸ ATM Q13315 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ MAPT P10636 2/20 0.35
▸ LMNA P02545 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ AKR1C4 P17516 1/20 0.32
▸ AKR1C3 P42330 1/20 0.32
▸ AKR1C2 P52895 1/20 0.32
▸ AKR1C1 Q04828 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ BCHE P06276 1/20 0.32
▸ ACHE P22303 1/20 0.32
▸ PDE9A O76083 1/20 0.31
▸ PDE1C Q14123 1/20 0.31
▸ P2RX4 Q99571 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23306885 0.92 KDM4E (0.36) KDM4EATML3MBTL1MAPTLMNA
SCHEMBL2620742 0.92 KDM4E (0.47) KDM4EATML3MBTL1ALDH1A1PTPN1
SCHEMBL2620744 0.84 KDM4E (0.43) KDM4EATML3MBTL1ALDH1A1PTPN1
SCHEMBL19938794 0.83 KDM4E (0.40) KDM4EATML3MBTL1MAPTLMNA
SCHEMBL18411836 0.83 KDM4E (0.36) KDM4EATML3MBTL1HDAC4
SCHEMBL16017469 0.81 L3MBTL1 (0.50) KDM4EATML3MBTL1MAPTHTT
SCHEMBL24715074 0.80 — —
SCHEMBL19764681 0.79 KDM4E (0.45) KDM4EATML3MBTL1ALDH1A1CYP19A1
SCHEMBL16865096 0.79 KDM4E (0.34) KDM4EATML3MBTL1
SCHEMBL24161903 0.78 KDM4E (0.33) KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11839140-B2 Metal complexes comprising diazabenzmidazolocarbene ligands and the use thereof in OLEDS UDC IRELAND LIMITED (IE) 2023-12-05 — — US disclosed
US-11839140-B2 Metal complexes comprising diazabenzmidazolocarbene ligands and the use thereof in OLEDS UDC IRELAND LIMITED (IE) 2023-12-05 — — US disclosed
US-11765967-B2 Highly efficient OLED devices with very short decay times UDC IRELAND LIMITED (IE) 2023-09-19 — — US disclosed
US-11765967-B2 Highly efficient OLED devices with very short decay times UDC IRELAND LIMITED (IE) 2023-09-19 — — US disclosed
US-20230026258-A1 Metal Complexes Comprising Diazabenzmidazolocarbene Ligands and the Use Thereof in OLEDS UDC IRELAND LTD (IE) 2023-01-26 — — US disclosed
EP-4060757-A1 HIGHLY EFFICIENT OLED DEVICES WITH VERY SHORT DECAY TIMES UDC Ireland Limited (IE) 2022-09-21 — — EP disclosed
US-20220149300-A1 HIGHLY EFFICIENT OLED DEVICES WITH VERY SHORT DECAY TIMES UDC IRELAND LTD (IE) 2022-05-12 — — US disclosed
US-20220144869-A1 HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS UDC IRELAND LIMITED (IE) 2022-05-12 — — US disclosed
EP-3304612-B1 HIGHLY EFFICIENT OLED DEVICES WITH VERY SHORT DECAY TIMES UDC IRELAND LTD (IE) 2022-05-04 — — EP disclosed
EP-3916822-A1 HIGHLY EFFICIENT OLED DEVICES WITH VERY SHORT DECAY TIMES UDC Ireland Limited (IE) 2021-12-01 — — EP disclosed
US-8691401-B2 Bridged benzimidazole-carbene complexes and use thereof in OLEDS BASF SE (DE) 2014-04-08 — — US disclosed
WO-2013068376-A1 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2013-05-16 — — WO disclosed
US-20130032766-A1 METAL COMPLEXES COMPRISING DIAZABENZIMIDAZOLOCARBENE LIGANDS AND THE USE THEREOF IN OLEDS BASF SE (DE) 2013-02-07 — — US disclosed
US-8362246-B2 Bispyrimidines for electronic applications BASF SE (DE) 2013-01-29 — — US disclosed
US-20120319050-A1 METAL COMPLEXES COMPRISING AZABENZIMIDAZOLE CARBENE LIGANDS AND THE USE THEREOF IN OLEDS BASF SE (DE) 2012-12-20 — — US disclosed
US-20120205645-A1 HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2012-08-16 — — US disclosed
US-20120149904-A1 BISPYRIMIDINES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2012-06-14 — — US disclosed
US-20120095222-A1 PHENANTHRO[9, 10-B]FURANS FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2012-04-19 — — US disclosed
US-20110309346-A1 ORGANIC ELECTRONIC DEVICES COMPRISING A LAYER COMPRISING AT LEAST ONE METAL ORGANIC COMPOUND AND AT LEAST ONE METAL OXIDE BASF SE (DE) 2011-12-22 — — US disclosed
US-20110253988-A1 BRIDGED BENZIMIDAZOLE-CARBENE COMPLEXES AND USE THEREOF IN OLEDS BASF SE (DE) 2011-10-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120319050-A1 METAL COMPLEXES COMPRISING AZABENZIMIDAZOLE CARBENE LIGANDS AND THE USE THEREOF IN OLEDS OCIAD1, OCIAD2, OXA1L KDM4E 4412/4885ATM 3454/4885L3MBTL1 3381/4885
US-20120205645-A1 HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS OCIAD2, OCIAD1, CLTB KDM4E 3813/4885ATM 4500/4885L3MBTL1 1656/4885
US-20120149904-A1 BISPYRIMIDINES FOR ELECTRONIC APPLICATIONS DPYD, TYMP, TYMS KDM4E 1622/4885ATM 2950/4885L3MBTL1 3766/4885
US-20220144869-A1 HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS OCIAD2, OCIAD1, CLTB KDM4E 4143/4885ATM 4604/4885L3MBTL1 1926/4885
US-20120095222-A1 PHENANTHRO[9, 10-B]FURANS FOR ELECTRONIC APPLICATIONS P2RY10, P2RY11, P2RY12 KDM4E 1775/4885ATM 4742/4885L3MBTL1 4549/4885
US-20130032766-A1 METAL COMPLEXES COMPRISING DIAZABENZIMIDAZOLOCARBENE LIGANDS AND THE USE THEREOF IN OLEDS OCIAD1, OCIAD2, DRD2 KDM4E 4587/4885ATM 3382/4885L3MBTL1 2826/4885
US-20110253988-A1 BRIDGED BENZIMIDAZOLE-CARBENE COMPLEXES AND USE THEREOF IN OLEDS CCND1, DRD2, CCND2 KDM4E 3589/4885ATM 3853/4885L3MBTL1 1507/4885
US-20230026258-A1 Metal Complexes Comprising Diazabenzmidazolocarbene Ligands and the Use Thereof in OLEDS OCIAD1, OCIAD2, DRD2 KDM4E 4573/4885ATM 3351/4885L3MBTL1 2835/4885
US-11839140-B2 Metal complexes comprising diazabenzmidazolocarbene ligands and the use thereof in OLEDS OCIAD1, OCIAD2, DRD2 KDM4E 4573/4885ATM 3351/4885L3MBTL1 2835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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