Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.75 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.62 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.61 |
| ▸ | KDM2B | Q8NHM5 | 11/20 | 0.49 |
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19383507 | 0.90 | KDM4C (0.71) | KDM4CPHF8KDM5BKDM2BKDM5A | |
| SCHEMBL16033935 | 0.85 | KDM4C (1.00) | KDM4CPHF8KDM5BKDM2BKDM5A | |
| SCHEMBL24244224 | 0.84 | KDM4C (0.71) | KDM4CPHF8KDM5BKDM2BKDM5A | |
| SCHEMBL20978909 | 0.84 | KDM4C (0.71) | KDM4CPHF8KDM5BKDM2BKDM5A | |
| SCHEMBL19383517 | 0.82 | KDM4C (0.67) | KDM4CPHF8KDM5BKDM2BKDM5A | |
| SCHEMBL18612971 | 0.81 | KDM4C (0.71) | KDM4CPHF8KDM5BKDM2BKDM5A | |
| SCHEMBL16033729 | 0.79 | PHF8 (0.69) | KDM4CPHF8KDM5BKDM2BKDM5A | |
| SCHEMBL20953968 | 0.77 | KDM4C (0.73) | KDM4CPHF8KDM5BKDM2BCYP19A1 | |
| SCHEMBL20978892 | 0.76 | KDM4C (0.63) | KDM4CPHF8KDM5BKDM2BKDM5A | |
| SCHEMBL16035025 | 0.76 | KDM4C (1.00) | KDM4CPHF8KDM5BKDM2BKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436445-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2023-09-06 | — | — | EP | disclosed |