Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14672533 | 0.88 | CYP3A4 (0.68) | ALDH1A1MEN1HPGDKMT2AMAPK1 | |
| SCHEMBL14672346 | 0.88 | CYP3A4 (0.68) | ALDH1A1MEN1HPGDKMT2AMAPK1 | |
| SCHEMBL7878024 | 0.88 | ALDH1A1 (0.54) | ALDH1A1MEN1HPGDKMT2AMAPK1 | |
| SCHEMBL20943379 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MEN1HPGDKMT2AMAPK1 | |
| SCHEMBL20943301 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MEN1HPGDKMT2AMAPK1 | |
| SCHEMBL3683407 | 0.87 | CYP3A4 (0.69) | ALDH1A1MEN1HPGDKMT2AMAPK1 | |
| SCHEMBL20943402 | 0.87 | MEN1 (0.54) | ALDH1A1MEN1HPGDKMT2APRSS1 | |
| SCHEMBL20943310 | 0.87 | MEN1 (0.54) | ALDH1A1MEN1HPGDKMT2APRSS1 | |
| SCHEMBL24733316 | 0.86 | SLC15A1 (0.49) | ALDH1A1MEN1HPGDKMT2AMAPK1 | |
| SCHEMBL22465659 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MEN1HPGDKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286902-A1 | LIPID NANOPARTICLE COMPOSITION | Suzhou Abogen Biosciences Co., Ltd. (CN) | 2023-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286902-A1 | LIPID NANOPARTICLE COMPOSITION | CETP, NPC1, LCAT | ALDH1A1 4587/4885MEN1 2081/4885HPGD 2816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.