Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24392100 | 0.86 | CA12 (0.33) | CA1CA2CA12CA14 | |
| SCHEMBL21210958 | 0.80 | CA1 (0.33) | CA1CA2CA12CA14CA9 | |
| SCHEMBL13553459 | 0.78 | MEN1 (0.38) | ALDH1A1 | |
| SCHEMBL25097442 | 0.76 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL17000149 | 0.76 | TSHR (0.33) | ALDH1A1 | |
| SCHEMBL27888843 | 0.73 | PMP22 (0.48) | ALDH1A1 | |
| SCHEMBL27888838 | 0.73 | PMP22 (0.48) | ALDH1A1 | |
| SCHEMBL24392092 | 0.73 | CA12 (0.34) | CA1CA2CA12CA14 | |
| SCHEMBL15172183 | 0.72 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL41726 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | CGAS, GLS2, GLS | CA1 3083/4885CA2 1016/4885CA12 3267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.