SCHEMBL26214565

SCHEMBL26214565

Cc1ccc([Si](c2ccccc2)(c2ccccc2)c2cccc(-c3nc(-c4ccccc4)nc(-c4cccc([Si](c5ccccc5)(c5ccccc5)c5ccccc5)c4)n3)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.48
RAB9A P51151 5/20 0.44
NPC1 O15118 4/20 0.44
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
GBA1 P04062 1/20 0.44
ALDH1A1 P00352 3/20 0.42
NFKB1 P19838 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
NR1H2 P55055 1/20 0.41
NR1H3 Q13133 1/20 0.41
LMNA P02545 2/20 0.41
XBP1 P17861 1/20 0.41
HTT P42858 1/20 0.41
ATM Q13315 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MAPT P10636 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
HPGD P15428 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24604422 0.89 L3MBTL1 (0.48) L3MBTL1RAB9ANPC1MEN1KMT2A
SCHEMBL21340666 0.89 L3MBTL1 (0.48) L3MBTL1RAB9ANPC1MEN1KMT2A
SCHEMBL20655518 0.89 L3MBTL1 (0.48) L3MBTL1RAB9ANPC1MEN1KMT2A
SCHEMBL30826299 0.89 L3MBTL1 (0.48) L3MBTL1RAB9ANPC1MEN1KMT2A
SCHEMBL24253166 0.89 L3MBTL1 (0.47) L3MBTL1RAB9ANPC1MEN1KMT2A
SCHEMBL25449490 0.88 MEN1 (0.46) L3MBTL1RAB9ANPC1MEN1KMT2A
SCHEMBL25449283 0.88 MEN1 (0.46) L3MBTL1RAB9ANPC1MEN1KMT2A
SCHEMBL23268103 0.88 MEN1 (0.48) L3MBTL1RAB9ANPC1MEN1KMT2A
SCHEMBL23268205 0.88 L3MBTL1 (0.47) L3MBTL1RAB9ANPC1MEN1KMT2A
SCHEMBL23268105 0.88 L3MBTL1 (0.47) L3MBTL1RAB9ANPC1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329089-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-12 US disclosed
US-20230292539-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-20230292593-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-20230279029-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329089-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NR1H2, OXER1, NR1H3 L3MBTL1 2221/4885RAB9A 677/4885NPC1 838/4885
US-20230279029-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, EHD1 L3MBTL1 327/4885RAB9A 1497/4885NPC1 1844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.