SCHEMBL26214955

SCHEMBL26214955

CC(C)(C)OC(=O)Oc1ccc(C(C)(C)c2ccc(OC(C)(C)C)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.60
KDM1A O60341 1/20 0.45
CA2 P00918 1/20 0.39
MAPT P10636 3/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ACACB O00763 2/20 0.38
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
RAB9A P51151 2/20 0.36
HTT P42858 2/20 0.36
NPC1 O15118 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
KDM4E B2RXH2 3/20 0.35
POLB P06746 1/20 0.35
CYP3A4 P08684 2/20 0.35
ESR1 P03372 1/20 0.35
AR P10275 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL198087 0.93 ELANE (0.68) ELANEKDM1ACA2MAPTTDP1
SCHEMBL5561643 0.88 ELANE (0.62) ELANEKDM1ACA2MAPTTDP1
SCHEMBL13866881 0.88 ELANE (0.62) ELANEKDM1ACA2MAPTTDP1
SCHEMBL12604846 0.87 ELANE (0.60) ELANEKDM1AMAPTTDP1L3MBTL1
SCHEMBL16977195 0.87 ELANE (0.60) ELANEKDM1ACA2MAPTTDP1
SCHEMBL14437649 0.87 ELANE (0.65) ELANEKDM1ACA2MAPTTDP1
SCHEMBL13845187 0.84 ELANE (0.57) ELANEKDM1ACA2MAPTTDP1
SCHEMBL22418303 0.84 ELANE (0.57) ELANEKDM1ACA2MAPTTDP1
SCHEMBL4061370 0.84 ELANE (0.81) ELANEKDM1ACA2MAPTTDP1
SCHEMBL21253991 0.83 LMNA (0.50) ELANEMAPTTDP1L3MBTL1ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250314-A1 COMPOSITION FOR FORMING A COATING FILM FOR REMOVING FOREIGN MATTERS NISSAN CHEMICAL CORPORATION (JP) 2023-08-10 US disclosed