Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 3/20 | 0.60 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.56 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.56 |
| ▸ | TACR1 | P25103 | 4/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30334922 | 1.00 | TEAD1 (0.60) | TEAD1CARM1PRMT6TACR1SCN9A | |
| SCHEMBL20566961 | 0.89 | TEAD1 (0.63) | TEAD1CARM1PRMT6TACR1SCN9A | |
| SCHEMBL25261179 | 0.86 | TEAD1 (0.52) | TEAD1TACR1SCN9AKMT2AMEN1 | |
| SCHEMBL9937172 | 0.83 | STS (0.50) | TACR1USP30 | |
| SCHEMBL710560 | 0.83 | TACR1 (0.50) | TEAD1CARM1PRMT6TACR1KMT2A | |
| SCHEMBL25253627 | 0.81 | SCN9A (0.50) | TEAD1TACR1SCN9AKMT2AUSP30 | |
| SCHEMBL25327924 | 0.81 | SCN9A (0.48) | TEAD1TACR1SCN9AUSP30 | |
| SCHEMBL24168673 | 0.81 | MGLL (0.50) | CARM1PRMT6TACR1KMT2AMEN1 | |
| SCHEMBL14701462 | 0.81 | TACR1 (0.49) | TEAD1TACR1KMT2AMEN1NPC1 | |
| SCHEMBL30334881 | 0.81 | MGLL (0.50) | CARM1PRMT6TACR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286904-A1 | INHIBITORS OF YAP/TAZ-TEAD ONCOPROTEINS, SYNTHESIS AND USE THEREOF | BRIDGENE BIOSCIENCES, INC. | 2023-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286904-A1 | INHIBITORS OF YAP/TAZ-TEAD ONCOPROTEINS, SYNTHESIS AND USE THEREOF | TEAD1, TEAD2, TEAD3 | TEAD1 1/4885CARM1 224/4885PRMT6 135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.