Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ADA | P00813 | 1/20 | 0.35 |
| ▸ | ADCY5 | O95622 | 3/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19575394 | 0.87 | NSD3 (0.53) | NSD2NSD3ADCY5 | |
| SCHEMBL19575471 | 0.87 | NSD3 (0.53) | NSD2NSD3ADCY5 | |
| SCHEMBL20974516 | 0.87 | NSD3 (0.53) | NSD2NSD3ADCY5 | |
| SCHEMBL19575466 | 0.85 | CDK1 (0.40) | NR3C1NSD2NSD3HRH4HRH3 | |
| SCHEMBL26212075 | 0.85 | CDK1 (0.40) | NR3C1NSD2NSD3HRH4HRH3 | |
| SCHEMBL26224018 | 0.80 | P2RY1 (0.42) | — | |
| SCHEMBL20973538 | 0.79 | LMNA (0.53) | NSD3ADCY5 | |
| SCHEMBL20972815 | 0.78 | ADCY5 (0.51) | NSD3ADCY5ALDH1A1 | |
| SCHEMBL19575403 | 0.78 | ADCY5 (0.51) | NSD3ADCY5ALDH1A1 | |
| SCHEMBL20975139 | 0.78 | NSD3 (0.57) | NSD2NSD3ADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452477-B1 | ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | B C I PHARMA (BE) | 2023-09-13 | — | — | EP | disclosed |