SCHEMBL262226

SCHEMBL262226

CC(=O)OOC(=O)C(C)C(C)=O

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
ALDH1A1 P00352 3/20 0.32
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11269137 1.00 TSHR (0.38) TSHRALDH1A1LMNAHSD17B10
SCHEMBL2129150 0.92 TSHR (0.36) TSHRALDH1A1LMNAHSD17B10
SCHEMBL248325 0.78 TSHR (0.41) TSHRALDH1A1LMNAHSD17B10
SCHEMBL28185638 0.77 TSHR (0.36) TSHR
SCHEMBL7127758 0.76 TSHR (0.47) TSHRALDH1A1LMNAHSD17B10
SCHEMBL9712204 0.76 TSHR (0.39) TSHRALDH1A1LMNAHSD17B10
SCHEMBL28808913 0.75 ALDH1A1 (0.37) TSHRALDH1A1LMNAHSD17B10
SCHEMBL22733760 0.74 TSHR (0.38) TSHRALDH1A1LMNAHSD17B10
SCHEMBL25442 0.72
SCHEMBL858078 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2534240-B1 YEAST MICROORGANISMS WITH REDUCED BY-PRODUCT ACCUMULATION FOR IMPROVED PRODUCTION OF FUELS, CHEMICALS, AND AMINO ACIDS GEVO INC (US) 2019-06-05 EP disclosed
US-9506074-B2 Yeast microorganisms with reduced by-product accumulation for improved production of fuels, chemicals, and amino acids GEVO, INC. (US) 2016-11-29 US disclosed
US-9012189-B2 Modified alcohol dehydrogenases for the production of fuels and chemicals GEVO, INC. (US) 2015-04-21 US disclosed
US-20140308721-A1 Cytosolic Isobutanol Pathway Localization for the Production of Isobutanol GEVO, INC. (US) 2014-10-16 US disclosed
US-20140212953-A1 YEAST MICROORGANISMS WITH REDUCED BY-PRODUCT ACCUMULATION FOR IMPROVED PRODUCTION OF FUELS, CHEMICALS, AND AMINO ACIDS GEVO, INC. (US) 2014-07-31 US disclosed
US-20140017748-A1 MODIFIED ALCOHOL DEHYDROGENASES FOR THE PRODUCTION OF FUELS AND CHEMICALS GEVO, INC. (US) 2014-01-16 US disclosed
WO-2013048599-A2 KETOL-ACID REDUCTOISOMERASES WITH IMPROVED PERFORMANCE PROPERTIES GEVO, INC. (US) 2013-04-04 WO disclosed
EP-2534240-A2 YEAST MICROORGANISMS WITH REDUCED BY-PRODUCT ACCUMULATION FOR IMPROVED PRODUCTION OF FUELS, CHEMICALS, AND AMINO ACIDS GEVO, Inc. (US) 2012-12-19 EP disclosed
US-8232089-B2 Cytosolic isobutanol pathway localization for the production of isobutanol GEVO, INC. (US) 2012-07-31 US disclosed
EP-2464736-A1 CYTOSOLIC ISOBUTANOL PATHWAY LOCALIZATION FOR THE PRODUCTION OF ISOBUTANOL Gevo, Inc. (US) 2012-06-20 EP disclosed
US-8153415-B2 Reduced by-product accumulation for improved production of isobutanol GEVO, INC. (US) 2012-04-10 US disclosed
US-8133715-B2 Reduced by-product accumulation for improved production of isobutanol GEVO, INC. (US) 2012-03-13 US disclosed
US-20110287500-A1 CYTOSOLIC ISOBUTANOL PATHWAY LOCALIZATION FOR THE PRODUCTION OF ISOBUTANOL GEVO, INC. (US) 2011-11-24 US disclosed
WO-2011142865-A2 YEAST MICROORGANISMS WITH REDUCED BY-PRODUCT ACCUMULATION FOR IMPROVED PRODUCTION OF FUELS, CHEMICALS, AND AMINO ACIDS GEVO, INC. (US) 2011-11-17 WO disclosed
US-20110275129-A1 Reduced by-product accumulation for improved production of isobutanol GEVO, INC. (US) 2011-11-10 US disclosed
US-20110236942-A1 Reduced by-product accumulation for improved production of isobutanol GEVO, INC. (US) 2011-09-29 US disclosed
US-20110201090-A1 Yeast microorganisms with reduced by-product accumulation for improved production of fuels, chemicals, and amino acids GEVO, INC. (US) 2011-08-18 US disclosed
US-20110201072-A1 Modified alcohol dehydrogenases for the production of fuels and chemicals GEVO, INC. (US) 2011-08-18 US disclosed
US-20110201073-A1 Reduced by-product accumulation for improved production of isobutanol GEVO, INC. (US) 2011-08-18 US disclosed
US-20110076733-A1 CYTOSOLIC ISOBUTANOL PATHWAY LOCALIZATION FOR THE PRODUCTION OF ISOBUTANOL GEVO, INC. (US) 2011-03-31 US disclosed