Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.58 |
| ▸ | CES1 | P23141 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27409673 | 0.84 | TTR (0.53) | TTRCES1CASP3DRD2HTR6 | |
| SCHEMBL16127516 | 0.82 | TTR (0.75) | TTRCES1CASP3DRD2HTR6 | |
| SCHEMBL12059596 | 0.78 | TTR (0.69) | TTRCES1CASP3DRD2HTR6 | |
| SCHEMBL11652592 | 0.75 | TTR (0.46) | TTRCES1CASP3DRD2HTR6 | |
| SCHEMBL28263 | 0.75 | CASP3 (0.81) | TTRCES1CASP3NR1H3NR1H2 | |
| SCHEMBL29511191 | 0.75 | CASP3 (0.81) | TTRCES1CASP3NR1H3NR1H2 | |
| SCHEMBL14288783 | 0.74 | TTR (0.53) | TTRCES1CASP3DRD2HTR6 | |
| SCHEMBL126628 | 0.74 | CES1 (1.00) | TTRCES1CASP3RAB9ATRPA1 | |
| SCHEMBL30077375 | 0.74 | TTR (0.69) | TTRCES1CASP3DRD2HTR6 | |
| SCHEMBL13039623 | 0.74 | TTR (0.69) | TTRCES1CASP3DRD2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141855-A1 | PROTEIN CONJUGATES WITH MULTIPLE PAYLOADS AND METHODS FOR MAKING THE SAME | GLYCO-THERAPY BIOTECHNOLOGY CO., LTD. (CN) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023065137-A1 | SITE-SPECIFIC GLYCOPROTEIN CONJUGATES AND METHODS FOR MAKING THE SAME | GLYCO-THERAPY BIOTECHNOLOGY CO., LTD. (CN) | 2023-04-27 | — | — | WO | disclosed |