SCHEMBL28263

SCHEMBL28263

CN1C(=O)c2ccccc2C1=O

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 1/20 0.81
TTR P02766 1/20 0.56
CES1 P23141 1/20 0.56
APP P05067 1/20 0.53
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
ALDH1A1 P00352 3/20 0.50
USP2 O75604 3/20 0.50
KEAP1 Q14145 2/20 0.50
NFE2L2 Q16236 2/20 0.50
ATM Q13315 1/20 0.50
KDM4E B2RXH2 1/20 0.50
HPGD P15428 1/20 0.50
SIRT2 Q8IXJ6 1/20 0.48
SIRT1 Q96EB6 1/20 0.48
GLS O94925 1/20 0.48
POLB P06746 2/20 0.48
NR1H2 P55055 2/20 0.47
NR1H3 Q13133 2/20 0.47
CASP1 P29466 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29511191 1.00 CASP3 (0.81) CASP3TTRCES1APPMEN1
Iodide SCHEMBL30725965 0.97 CASP3 (0.77) CASP3TTRCES1APPMEN1
SCHEMBL29025703 0.97 CASP3 (0.77) CASP3TTRCES1APPMEN1
Hydrogen Sulfide SCHEMBL11098631 0.97 CASP3 (0.77) CASP3TTRCES1APPMEN1
Water SCHEMBL9398503 0.97 CASP3 (0.77) CASP3TTRCES1APPMEN1
Hydrogen Sulfide SCHEMBL11121709 0.97 CASP3 (0.77) CASP3TTRCES1APPMEN1
Hydrochloric Acid SCHEMBL7736926 0.97 CASP3 (0.77) CASP3TTRCES1APPMEN1
SCHEMBL21196435 0.90 CASP3 (0.68) CASP3TTRCES1APPMEN1
SCHEMBL13442852 0.90 CASP3 (1.00) CASP3TTRCES1APPMEN1
Phthalimide SCHEMBL10397202 0.88 GSK3B (0.68) CASP3TTRCES1APPMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10731 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062607-A1 TWO-DIMENSIONAL LATTICE CONFINED SINGLE-MOLECULE-LIKE AGGREGATES PURDUE RESEARCH FOUNDATION (US) 2026-03-05 US claimed
CN-115667208-B Process for preparing dianhydride 乔拉根·马尼 2025-03-11 CN claimed
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US claimed
US-20250015331-A1 ION EXCHANGE LIQUID FILM FLOW BATTERY UNIV WESTLAKE (CN) 2025-01-09 US claimed
CN-119098120-A Synthesis system and process for 4-nitro-N-methylphthalimide 大连微凯化学有限公司 2024-12-10 CN claimed
EP-4435910-A1 ION EXCHANGE LIQUID FILM FLOW BATTERY Westlake University (CN) 2024-09-25 EP claimed
CN-118221568-A Method for preparing N-alkyl-4-nitrophthalimide by multistage series-parallel microreactors 常州大学 2024-06-21 CN claimed
CN-118221567-A Method for synthesizing N-alkyl-4-nitrophthalimide by multistage series-parallel gas-liquid microreactor 常州大学 2024-06-21 CN claimed
US-20240174876-A1 NONAQUEOUS INK COMPOSITION, INK SET, RECORDING METHOD USING SAME, METHOD FOR PRODUCING RECORDED MATTER, RECORDED MATTER, AND INKJET RECORDING DEVICE DNP FINE CHEMICALS CO., LTD. (JP) 2024-05-30 US claimed
CN-118084674-A Method for preparing deuterated methylamine hydrochloride by using methyl triflate-D3 西安瑞联新材料股份有限公司 2024-05-28 CN claimed
US-3962276-A ENZYME INHIBITORS ELI LILLY AND COMPANY (US) 1976-06-08 US claimed
US-3962226-A 3-NITROOXYCEPHAM COMPOUNDS AND PROCESS FOR PREPARING DESACETOXYCEPHALOSPORINS THEREFROM ELI LILLY AND COMPANY (US) 1976-06-08 US claimed
US-3960851-A Preparation of desacetoxy-cephalosporin sulfoxides from penicillin sulfoxides ELI LILLY AND COMPANY (US) 1976-06-01 US claimed
US-3960844-A Preparation of 6-acylamino-2-methyl-2-halomethyl penams ELI LILLY AND COMPANY (US) 1976-06-01 US claimed
US-3953437-A Process of preparing cephalosporanic acid ester derivatives YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1976-04-27 US claimed
US-3944545-A Process for preparing desacetoxycephalosporins ELI LILLY AND COMPANY (US) 1976-03-16 US claimed
US-3935198-A BY HEATING THE PENICILLIN SULFOXIDE YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1976-01-27 US claimed
US-3933852-A Process for making N-methyl nitrophthalimides GENERAL ELECTRIC COMPANY (US) 1976-01-20 US claimed
US-3932387-A Process for the conversion of 3-methyl-3-hydroxycepham compounds ELI LILLY AND COMPANY (US) 1976-01-13 US claimed
US-3932391-A Cephalosporin isocyanates AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-13 US claimed