Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.45 |
| ▸ | YTHDC1 | Q96MU7 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.40 |
| ▸ | PDE8A | O60658 | 3/20 | 0.38 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19575638 | 0.92 | PPARG (0.46) | CHKAYTHDC1HDAC1HDAC6HDAC3 | |
| SCHEMBL19575672 | 0.91 | CHKA (0.46) | CHKAYTHDC1HDAC1HDAC6HDAC3 | |
| SCHEMBL19553670 | 0.90 | YTHDC1 (0.47) | CHKAYTHDC1HDAC1HDAC6HDAC3 | |
| SCHEMBL19575381 | 0.90 | CHKA (0.46) | CHKAYTHDC1HDAC1HDAC6HDAC3 | |
| SCHEMBL19553600 | 0.89 | PPARG (0.48) | CHKAYTHDC1HDAC1HDAC6HDAC3 | |
| SCHEMBL20974433 | 0.89 | PADI3 (0.47) | CHKAYTHDC1HDAC1HDAC6HDAC3 | |
| SCHEMBL19575525 | 0.88 | YTHDC1 (0.51) | CHKAYTHDC1HDAC1HDAC6HDAC3 | |
| SCHEMBL19575483 | 0.88 | CHKA (0.43) | CHKAYTHDC1HDAC1HDAC6HDAC3 | |
| SCHEMBL19575468 | 0.88 | CHKA (0.45) | CHKAYTHDC1HDAC1HDAC6HDAC3 | |
| SCHEMBL20973900 | 0.88 | CHKA (0.45) | CHKAYTHDC1HDAC1HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452477-B1 | ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | B C I PHARMA (BE) | 2023-09-13 | — | — | EP | disclosed |