SCHEMBL26224398

SCHEMBL26224398

CC(C)COc1cc(P)cc(CCCCC(=O)C(C)C)c1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 17/20 0.36
▸ CNR1 P21554 16/20 0.36
▸ FOS P01100 2/20 0.36
▸ JUN P05412 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26203889 0.85 CNR2 (0.39) CNR2CNR1FOSJUN
SCHEMBL26203868 0.84 CNR2 (0.38) CNR2CNR1FOSJUN
SCHEMBL22525342 0.84 FFAR4 (0.40) CNR2CNR1FOSJUN
SCHEMBL23845447 0.81 PPARA (0.49) CNR2CNR1FOSJUN
SCHEMBL24847857 0.80 PPARA (0.51) CNR2CNR1FOSJUN
SCHEMBL26203900 0.76 FOS (0.47) FOSJUN
SCHEMBL25122747 0.73 CNR2 (0.46) CNR2CNR1
SCHEMBL25122728 0.73 FOS (0.41) CNR2FOSJUN
SCHEMBL25123317 0.72 CNR2 (0.45) CNR2CNR1
SCHEMBL25123387 0.72 CNR2 (0.45) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240016942-A1 STAT DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2024-01-18 — — US disclosed
US-11746120-B2 Stat degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2023-09-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11746120-B2 Stat degraders and uses thereof STAT4, STAT1, STAT3 CNR2 2461/4885CNR1 2602/4885FOS 3232/4885
US-20240016942-A1 STAT DEGRADERS AND USES THEREOF STAT4, STAT1, STAT3 CNR2 2461/4885CNR1 2602/4885FOS 3232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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