Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 20/20 | 0.79 |
| ▸ | GABRB2 | P47870 | 20/20 | 0.79 |
| ▸ | GABRD | O14764 | 19/20 | 0.79 |
| ▸ | GABRA4 | P48169 | 19/20 | 0.79 |
| ▸ | GABRP | O00591 | 18/20 | 0.79 |
| ▸ | GABRB1 | P18505 | 18/20 | 0.79 |
| ▸ | GABRG2 | P18507 | 18/20 | 0.79 |
| ▸ | GABRB3 | P28472 | 18/20 | 0.79 |
| ▸ | GABRA5 | P31644 | 18/20 | 0.79 |
| ▸ | GABRA3 | P34903 | 18/20 | 0.79 |
| ▸ | GABRA2 | P47869 | 18/20 | 0.79 |
| ▸ | GABRE | P78334 | 18/20 | 0.79 |
| ▸ | GABRA6 | Q16445 | 18/20 | 0.79 |
| ▸ | GABRG1 | Q8N1C3 | 18/20 | 0.79 |
| ▸ | GABRG3 | Q99928 | 18/20 | 0.79 |
| ▸ | GABRQ | Q9UN88 | 18/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16190892 | 0.88 | GABRA1 (0.81) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL14871146 | 0.88 | GABRP (1.00) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL21091386 | 0.88 | GABRP (1.00) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL23346583 | 0.88 | GABRP (1.00) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL19650972 | 0.88 | GABRP (1.00) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL23468933 | 0.88 | GABRP (1.00) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL3124023 | 0.88 | GABRP (1.00) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL23344276 | 0.88 | GABRP (1.00) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL22516226 | 0.88 | GABRA1 (0.81) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL17792263 | 0.88 | GABRA1 (0.81) | GABRA1GABRB2GABRDGABRA4GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3481845-B1 | C17, C20, AND C21 SUBSTITUTED NEUROACTIVE STEROIDS AND THEIR METHODS OF USE | SAGE THERAPEUTICS INC (US) | 2023-09-13 | — | — | EP | disclosed |