SCHEMBL2622756

SCHEMBL2622756

CNC(=O)c1cc(C(c2ccc(C(=O)O)c(C(=O)Nc3cc(C(c4ccc(O)c(C)c4)(C(F)(F)F)C(F)(F)F)ccc3O)c2)(C(F)(F)F)C(F)(F)F)ccc1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SORT1 Q99523 10/20 0.43
GAA P10253 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
AKT1 P31749 1/20 0.40
TMPRSS4 Q9NRS4 2/20 0.38
KCNMA1 Q12791 3/20 0.38
TAS2R14 Q9NYV8 1/20 0.37
NR1H4 Q96RI1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL822603 0.90 SORT1 (0.42) SORT1GAAMEN1KMT2AAKT1
SCHEMBL13292496 0.88 TDP1 (0.39) SORT1GAAAKT1TMPRSS4NR1H4
SCHEMBL12917926 0.85 AKT1 (0.43) SORT1GAAMEN1KMT2AAKT1
SCHEMBL18968832 0.83 SORT1 (0.40) SORT1MEN1KMT2ANR1H4
SCHEMBL21360957 0.83 AKT1 (0.39) MEN1KMT2AAKT1TMPRSS4KCNMA1
SCHEMBL2605530 0.82 KMT2A (0.49) GAAMEN1KMT2AAKT1KCNMA1
SCHEMBL19986794 0.81 GAA (0.51) GAAMEN1KMT2ATMPRSS4KCNMA1
SCHEMBL15611032 0.79 KMT2A (0.46) GAAMEN1KMT2AKCNMA1
SCHEMBL13949357 0.78 HPGD (0.48) MEN1KMT2AAKT1KCNMA1NR1H4
SCHEMBL22954898 0.78 SORT1 (0.42) SORT1NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8163071-B2 Hollow fiber, dope composition for forming hollow fiber, and method of preparing hollow fiber using the same IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (KR) 2012-04-24 US disclosed
US-20090297850-A1 HOLLOW FIBER, DOPE COMPOSITION FOR FORMING HOLLOW FIBER, AND METHOD OF MAKING HOLLOW FIBER USING THE SAME IUCF-HYU(INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (KR) 2009-12-03 US disclosed
US-20090286078-A1 POLYIMIDES DOPE COMPOSITION, PREPARATION METHOD OF HOLLOW FIBER USING THE SAME AND HOLLOW FIBER PREPARED THEREFROM INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2009-11-19 US disclosed
US-20090286904-A1 POLYAMIC ACIDS DOPE COMPOSITION, PREPARATION METHOD OF HOLLOW FIBER USING THE SAME AND HOLLOW FIBER PREPARED THEREFROM INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2009-11-19 US disclosed
US-20090282982-A1 HOLLOW FIBER, DOPE COMPOSITION FOR FORMING HOLLOW FIBER, AND METHOD OF PREPARING HOLLOW FIBER USING THE SAME IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (KR) 2009-11-19 US disclosed