SCHEMBL2622758

SCHEMBL2622758

Cc1cc(C(c2ccc(O)c(N3C(=O)c4ccc(C(c5ccc6c(c5)C(=O)N(C)C6=O)(C(F)(F)F)C(F)(F)F)cc4C3=O)c2)(C(F)(F)F)C(F)(F)F)ccc1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.41
ESR2 Q92731 4/20 0.41
NR1H2 P55055 3/20 0.38
NR1H3 Q13133 3/20 0.38
TYMS P04818 1/20 0.37
HSP90AA1 P07900 2/20 0.36
MEN1 O00255 2/20 0.36
MAPT P10636 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
TSHR P16473 1/20 0.36
NFKB1 P19838 1/20 0.36
CYP2C19 P33261 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
KCNMA1 Q12791 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
APP P05067 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9891724 0.96 ESR1 (0.43) ESR1ESR2NR1H2NR1H3TYMS
SCHEMBL13966982 0.95 ESR1 (0.38) ESR1ESR2NR1H2NR1H3TYMS
SCHEMBL13292495 0.92 BRD4 (0.38) ESR1ESR2NR1H2NR1H3TYMS
SCHEMBL15593256 0.91 APP (0.39) ESR1ESR2NR1H2NR1H3TYMS
SCHEMBL25969184 0.90 MEN1 (0.38) ESR1ESR2NR1H2NR1H3TYMS
SCHEMBL822316 0.90 ESR1 (0.40) ESR1ESR2NR1H2NR1H3TYMS
SCHEMBL9610064 0.88 TYMS (0.47) ESR1ESR2NR1H2NR1H3TYMS
SCHEMBL21933189 0.87 PKM (0.38) ESR1ESR2NR1H2NR1H3TYMS
SCHEMBL12367660 0.85 ESR1 (0.43) ESR1ESR2NR1H2NR1H3MEN1
SCHEMBL17898388 0.85 BRD4 (0.47) ESR1ESR2TYMSMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230260787-A1 COMPOSITION FOR FORMING PROTECTIVE FILM AGAINST ALKALINE AQUEOUS HYDROGEN PEROXIDE, SUBSTRATE FOR PRODUCING SEMICONDUCTOR APPARATUS, METHOD FOR FORMING PROTECTIVE FILM, AND METHOD FOR FORMING PATTERN SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-17 US disclosed
US-20120135251-A1 PHOTOSENSITIVE POLYIMIDE HAVING SILICON MODIFIED GROUP, ADHESIVE COMPOSITION AND SEMICONDUCTOR PACKAGE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-05-31 US disclosed
US-8163071-B2 Hollow fiber, dope composition for forming hollow fiber, and method of preparing hollow fiber using the same IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (KR) 2012-04-24 US disclosed
US-20090297850-A1 HOLLOW FIBER, DOPE COMPOSITION FOR FORMING HOLLOW FIBER, AND METHOD OF MAKING HOLLOW FIBER USING THE SAME IUCF-HYU(INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (KR) 2009-12-03 US disclosed
US-20090286078-A1 POLYIMIDES DOPE COMPOSITION, PREPARATION METHOD OF HOLLOW FIBER USING THE SAME AND HOLLOW FIBER PREPARED THEREFROM INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2009-11-19 US disclosed
US-20090286904-A1 POLYAMIC ACIDS DOPE COMPOSITION, PREPARATION METHOD OF HOLLOW FIBER USING THE SAME AND HOLLOW FIBER PREPARED THEREFROM INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2009-11-19 US disclosed
US-20090282982-A1 HOLLOW FIBER, DOPE COMPOSITION FOR FORMING HOLLOW FIBER, AND METHOD OF PREPARING HOLLOW FIBER USING THE SAME IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (KR) 2009-11-19 US disclosed
US-7485405-B2 Photo-curable resin composition comprising a polyimide, a process for forming a pattern therewith, and a substrate protecting film SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-02-03 US disclosed
US-7485405-B2 Photo-curable resin composition comprising a polyimide, a process for forming a pattern therewith, and a substrate protecting film SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-02-03 US disclosed