Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26229443 | 0.87 | TSHR (0.44) | MEN1KMT2AADORA1SMN1; SMN2TSHR | |
| SCHEMBL26229442 | 0.83 | PKM (0.36) | MEN1KMT2ATSHRCYP2C9CYP1A2 | |
| SCHEMBL26545444 | 0.82 | TSHR (0.44) | MEN1KMT2AADORA1TSHRHTT | |
| SCHEMBL26545442 | 0.80 | HTT (0.42) | SMN1; SMN2TSHRHTTHPGDALDH1A1 | |
| SCHEMBL26545440 | 0.79 | DEGS1 (0.42) | SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL26209321 | 0.78 | KDM4E (0.38) | MEN1KMT2ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL12392894 | 0.75 | MAP4K4 (0.46) | HTTGAAHPGDALDH1A1 | |
| SCHEMBL26545741 | 0.74 | EGLN2 (0.34) | TSHR | |
| SCHEMBL26545438 | 0.73 | EGLN2 (0.34) | TSHR | |
| SCHEMBL12392887 | 0.66 | RET (0.41) | ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168194-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-09-07 | — | — | WO | disclosed |